Anthracyclines
Doxorubicin hydrochloride
CAS: 25316-40-9 Molecular Formula: C27H30ClNO11 Molecular Weight (g/mol): 579.98 MDL Number: MFCD00077757,MFCD00077757,MFCD00941448 InChI Key: MWWSFMDVAYGXBV-FGBJBKNOSA-N Synonym: doxorubicin hydrochloride,adriamycin,doxorubicin hcl,adriacin,adriblastina,rubex,adriamycin hydrochloride,adriblastin,adriamycin pfs PubChem CID: 129626538 IUPAC Name: hydrogen (8S,10S)-10-[(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy]-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione chloride SMILES: [H+].[Cl-].COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3OC3CC(N)C(O)C(C)O3)C(=O)CO)C(O)=C1C2=O
Doxorubicin hydrochloride, MP Biomedicals™
CAS: 25316-40-9 Molecular Formula: C27H30ClNO11 Molecular Weight (g/mol): 579.98 MDL Number: MFCD00077757,MFCD00077757,MFCD00941448 InChI Key: MWWSFMDVAYGXBV-FGBJBKNOSA-N Synonym: doxorubicin hydrochloride,adriamycin,doxorubicin hcl,adriacin,adriblastina,rubex,adriamycin hydrochloride,adriblastin,adriamycin pfs PubChem CID: 129626538 IUPAC Name: hydrogen (8S,10S)-10-[(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy]-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione chloride SMILES: [H+].[Cl-].COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3OC3CC(N)C(O)C(C)O3)C(=O)CO)C(O)=C1C2=O
Daunorubicin hydrochloride
CAS: 23541-50-6 Molecular Formula: C27H30ClNO10 Molecular Weight (g/mol): 563.984 MDL Number: MFCD04974507 InChI Key: GUGHGUXZJWAIAS-QQYBVWGSSA-N Synonym: daunorubicin hydrochloride,daunorubicin hcl,daunomycin hydrochloride,daunoblastina,rubidomycin hydrochloride,daunorubicinol hydrochloride,daunoblastin,rubomycin,ondena,daunomycin chlorohydrate PubChem CID: 62770 IUPAC Name: (7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride SMILES: CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)C)O)N)O.Cl
Doxorubicin Hydrochloride 95.0+%, TCI America™
CAS: 25316-40-9 Molecular Formula: C27H30ClNO11 Molecular Weight (g/mol): 579.98 MDL Number: MFCD00077757,MFCD00077757,MFCD00941448 InChI Key: MWWSFMDVAYGXBV-FGBJBKNOSA-N Synonym: doxorubicin hydrochloride,adriamycin,doxorubicin hcl,adriacin,adriblastina,rubex,adriamycin hydrochloride,adriblastin,adriamycin pfs PubChem CID: 129626538 IUPAC Name: hydrogen (8S,10S)-10-[(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy]-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione chloride SMILES: [H+].[Cl-].COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3OC3CC(N)C(O)C(C)O3)C(=O)CO)C(O)=C1C2=O
Daunorubicin Hydrochloride 98.0+%, TCI America™
CAS: 23541-50-6 Molecular Formula: C27H30ClNO10 Molecular Weight (g/mol): 563.984 MDL Number: MFCD04974507 InChI Key: GUGHGUXZJWAIAS-QQYBVWGSSA-N Synonym: daunorubicin hydrochloride,daunorubicin hcl,daunomycin hydrochloride,daunoblastina,rubidomycin hydrochloride,daunorubicinol hydrochloride,daunoblastin,rubomycin,ondena,daunomycin chlorohydrate PubChem CID: 62770 IUPAC Name: (7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride SMILES: CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)C)O)N)O.Cl
Medchemexpress LLC Daunorubicin hydrochloride | 23541-50-6 | MFCD04974507 | 99.7% | 563.98 g/mol | C27H30ClNO10 | 5 MG
Daunorubicin hydrochloride is an anthracycline antibiotic and potent cytotoxic research compound that intercalates DNA and inhibits topoisomerase II. Provided as the hydrochloride salt for research use, it is commonly used in oncology and biochemical studies where controlled, small-quantity reagent handling and high-purity material are required.
- Anthracycline antibiotic with cytotoxic activity.
- Potent topoisomerase II inhibitor causing DNA intercalation.
- Hydrochloride salt form for enhanced solubility and handling.
- High purity suitable for analytical and biological assays.
- Molecular weight 563.98 g/mol; formula C27H30ClNO10.
- Supplied in small measured quantities for research workflows.
Medchemexpress LLC Doxorubicin hydrochloride | 25316-40-9 | MFCD00077757 | 99.3% | 579.98 g/mol | C27H30ClNO11 | 10 MG
Doxorubicin hydrochloride is an anthracycline antibiotic with cytotoxic activity supplied as a high-purity analytical standard for laboratory research. It functions as a DNA intercalator and inhibits topoisomerases I and II, making it useful as a biochemical reagent and reference in cell-based assays and analytical method development.
- High purity (99.33%) suitable for analytical applications.
- Confirmed identity: CAS 25316-40-9, molecular weight 579.98 g/mol.
- Available in multiple package sizes, including 10 mg.
- Acts as a DNA intercalator and topoisomerase I/II inhibitor.
- Suitable for biochemical assays, cell-based studies, and analytical standards.
Medchemexpress LLC BIIE-0246 hydrochloride | 246146-55-4 | MFCD04113026 | >98.0% | 896.0 g/mol | C49H57N11O6 | 5 MG
BIIE-0246 hydrochloride is a selective, non-peptide antagonist of the neuropeptide Y Y2 receptor supplied as the hydrochloride salt for research use. It is used in pharmacological studies to probe NPY-mediated signaling and is provided at high purity for in vitro and in vivo experiments.
- Selective NPY Y2 receptor antagonist
- High purity (>98.0%) suitable for research
- Hydrochloride salt for improved aqueous solubility
- Molecular formula C49H57N11O6; molar mass 896.0 g/mol
- Available in small research pack sizes, for example 5 MG
Selleck Chemical LLC Doxorubicin (DOX) HCl S1208-1g
Doxorubicin (DOX) HCl is an antibiotic agent that inhibits human DNA topoisomerase I and topoisomerase II with IC50s of 0 8 M and 2 67 M respectively Doxorubicin reduces basal phosphorylation of AMPK Doxorubicin is used in the concomitant treatment of HIV-infected patients but is found to be at high risk of HBV reactivation This product may precipitate when dissolved in PBS solution It is recommended to prepare the stock solution in pure water and dilute with either pure water or saline to obtain the working solution Doxorubicin (Adriamycin) HCl can be used to induce animal models of kidney disease
Medchemexpress LLC Doxorubicin (hydrochloride) | 25316-40-9 | MFCD00077757 | C27H30ClNO11 | 2 G
Doxorubicin hydrochloride is a cytotoxic anthracycline antibiotic and a potent anti-cancer chemotherapy agent. It functions as a human DNA topoisomerase I and II inhibitor, reducing basal phosphorylation of AMPK and inducing apoptosis and autophagy. This orange-red crystalline solid is isolated from cultures of Streptomyces peucetius var. caesius.
- Potent human DNA topoisomerase I and II inhibitor
- Reduces basal phosphorylation of AMPK
- Induces apoptosis and autophagy
- Functions as a DNA intercalator
- Acts as a fluorescent dye
- Exhibits antitumor and antibiotic activity
- Inhibits reverse transcriptase and RNA polymerase
Sigma Aldrich Fine Chemicals Biosciences Naltrindole hydrochloride50MG
Naltrindole hydrochloride50MG
Medchemexpress LLC Daunorubicin (hydrochloride) | 23541-50-6 | 99.7% | 25 MG
Daunorubicin hydrochloride is a potent topoisomerase II inhibitor with significant anti-tumor activity. This anthracycline antibiotic inhibits both DNA and RNA synthesis, functioning as a cytotoxin that reduces cancer cell viability and induces apoptosis and necrosis. It is utilized in research for various infections and cancers, including leukemia, non-Hodgkin lymphomas, Ewing's sarcoma, and Wilms' tumor. The compound is a pink to red solid, stable under recommended storage conditions, with a melting point of 190°C.
- Target: topoisomerase, DNA/RNA synthesis, ADC payload, bacterial, autophagy, apoptosis, antibiotic
- Research areas: infection, neurological disease, cancer
- CAS number: 23541-50-6
- Molecular formula: C27H30ClNO10
- Molecular weight: 563.98
- Appearance: pink to red solid
- Purity (LCMS): 99.7%
- Melting point: 190°C
Sigma Aldrich Fine Chemicals Biosciences Doxorubicin hydrochloride10MG
Chemical structure tetracycline
Medchemexpress LLC Doxorubicin (hydrochloride) | 25316-40-9 | C27H30ClNO11 | 25 MG
Doxorubicin hydrochloride (Hydroxydaunorubicin hydrochloride; ADR) is a cytotoxic anthracycline antibiotic and an anti-cancer chemotherapy agent. It functions as a potent human DNA topoisomerase I and topoisomerase II inhibitor, reducing basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Additionally, it induces apoptosis and autophagy.
- Cytotoxic anthracycline antibiotic
- Anti-cancer chemotherapy agent
- Potent human DNA topoisomerase I and II inhibitor
- Reduces basal phosphorylation of AMPK and acetyl-CoA carboxylase
- Induces apoptosis and autophagy
- Suitable for neutral or weakly acidic solvents
- Melting/freezing point of 216°C
- For research use only