Isotype Controls and Standards
Quantikine Immunoassay Control Set 1064 for Human HS CTLA-4, R&D Systems™
Immunoassay Control Set
Quantikine Immunoassay Control 1049 for Human IFN-alpha AS , R&D Systems™
Immunoassay Control Set
Quantikine Immunoassay Control Set 887 Human TIM-3, R&D Systems™
For use with catalog number DTIM30
Cayman Chemical HS-014 (trifluoroacetate salt), Purity: ≥98%, 25 mg
An MC4R antagonist (Ki = 3.16 nM); selective for MC4R over MC1R, MC3R, and MC5R (Kis = 108, 54.4, and 694 nM, respectively); inhibits α-MSH-induced cAMP accumulation induced by in COS-1 cells expressing MC4R in a concentration-dependent manner; increases food intake in free-feeding rats at 1 or 3 nmol/animal, i.c.v; increases the latency to tail withdrawal in the tail-flick test, as well as inhibits morphine withdrawal-induced decreases in the latency to tail withdrawal in the tail-flick test, in rats at 0.008 ng/animal, i.c.v.; reduces immobility time in the forced swim test, as well as increases time in the open area and reduces the number of droppings in an open field test, in rats at 100 µg/animal
Cayman Chemical 4-Methyl-7-(4-nitro-2-(trifluoromethyl)phenoxy)-2H-chromen-2-one, Purity: ≥98%, CAS: 433254-36-5, 25 mg
A turn-on fluorescent probe for H2S; excited at 348 nm in DMSO and fluorescence intensity increases in the presence of HS-; selective for HS- over cysteine, AcO-, F-, H2PO4-, Cl-, Br-, and I- and is not cytotoxic up to a concentration of 150 µg/ml
Cayman Chemical Savolitinib, Purity: ≥98%, CAS: 1313725-88-0, 25 mg
An inhibitor of c-Met (IC50 = 5 nM); selectivity inhibits c-Met over 274 other kinases at 1 µM; inhibits c-Met autophosphorylation in NCI H441 human NSCLC cells (IC50 = 3 nM); inhibits HGF-induced growth of NCI H441 cells (IC50 = 6 nM); inhibits proliferation in a panel of gastric cancer cells with dysregulated c-Met (EC50s = 0.6-14.7 nM); inhibits intratumor c-Met autophosphorylation by 94% and reduces tumor growth in a Hs 746T human stomach cancer mouse xenograft model at 3 mg/kg