Vector M.O.M. Kits contain a proprietary Mouse IgG Blocking Reagent that greatly reduces endogenous mouse IgG background when staining mouse primary antibodies on mouse tissue. Vector M.O.M. Immunodetection Kits are useful in any mouse-on-mouse application, such as studies in genetically engineered mice, including transgenic and knock-out models, and mouse xenografts. M.O.M. Kits can be also used in multiple antigen staining protocols to localize two different mouse primary antibodies on the same mouse tissue sections using fluorescent or enzyme-based detection systems. The M.O.M. Basic Kit is designed to be used with a user-provided horseradish peroxidase, alkaline phosphatase, or fluorescent dye-labeled avidin or streptavidin conjugate that is compatible with M.O.M. Biotinylated Anti-Mouse IgG secondary antibody.