Protease Inhibitors and Phosphatase Inhibitors
Echelon Biosciences Research Labs Caspase 1 Substrate - 5 mg,
Caspase 1 Substrate - 5mg , Ac-Trp-Glu-Ala-Asp-pNA Category/Application: Enzyme Substrates This item is non returnable
Echelon Biosciences Research Labs Caspase 3 Substrate - 5 mg,
Caspase 3 Substrate - 5mg , Ac-Asp-Glu-Val-Asp-4-methoxy-2-naphthylamide Category/Application: Enzyme Substrates This item is non returnable
Echelon Biosciences Research Labs Granzyme B Substrate - 0.5 mg,
Granzyme B Substrate - 0.5mg , Ac-Ile-Glu-Pro-Asp-AFC Category/Application: Enzyme Substrates This item is non returnable
Echelon Biosciences Research Labs Caspase 8 Substrate - 5 mg, CAS#: 211990-57-7
Caspase 8 Substrate - 5mg , Ac-Ile-Glu-Thr-Asp-AFC Category/Application: Enzyme Substrates This item is non returnable
Echelon Biosciences Research Labs Caspase 2/3 Substrate - 5 mg,
Caspase 2/3 Substrate - 5mg , Ac-Leu-Asp-Glu-Ser-Asp-AMC Category/Application: Enzyme Substrates This item is non returnable
Echelon Biosciences Research Labs Cathepsin B II Inhibitor - 5 mg, CAS#: 147600-40-6
Cathepsin B II Inhibitor - 5mg , Acetyl-Leu-Val-Lys-Aldehyde Category/Application: Enzyme Substrates This item is non returnable
Echelon Biosciences Research Labs Cathepsin L Inhibitor - 5 mg, CAS#: 161709-56-4
Cathepsin L Inhibitor - 5mg , 1-Naphthalene-sulfonyl-Ile-Trp-Aldehyde Category/Application: Enzyme Substrates This item is non returnable
Echelon Biosciences Research Labs MMP 2 Substrate, fluorogenic - 1 mg,
MMP 2 Substrate, fluorogenic - 1mg , Mca-Pro-Leu-Ala-Nva-Dpa-Ala-Arg-NH2 Category/Application: Enzyme Substrates This item is non returnable
Echelon Biosciences Research Labs PKC Isoenzyme Inhibitor PKC Y translocation peptide - 1 mg,
PKC Isoenzyme Inhibitor PKC Y translocation peptide - 1mg , Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr-OH Category/Application: Inhibitor This item is non returnable
Echelon Biosciences Research Labs BODIPY TMR-PI(5)P 50 ug
BODIPY TMR PI(5)P (BODIPY TMR Phosphatidylinositol 5-phosphate) is a water soluble analog of PI(5)P labeled with the orange fluorophore, Bodipy-TMR, at the sn-1 position.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 5-phosphate (PI(5)P) is a rare lipid found in the nucleus that can bind the PHD finger of the nuclear adapter protein ING2. PI(5)P is phosphorylated to PI(4,5)P2 by Type II PIP kinases. This item is non returnable
Echelon Biosciences Research Labs Amyloid Blocker - 5 mg, CAS#: 189064-06-0
Beta Amyloid (13-16), human - 5mg , His-His-Gln-Lys-OH Category/Application: Alzheimer's This item is non returnable
Echelon Biosciences Research Labs Caspase 1 Substrate - 5 mg, CAS#: 219137-85-6
Caspase 1 Substrate - 5mg , Ac-Val-Ala-Asp-AFC Category/Application: Enzyme Substrates This item is non returnable
Echelon Biosciences Research Labs MMP 13 Substrate, fluorogenic - 1 mg,
MMP 13 Substrate, fluorogenic - 1mg , Mca-Pro-Cha-Gly-Nva-His-Ala-Dpa-NH2 Category/Application: Enzyme Substrates This item is non returnable
Echelon Biosciences Research Labs MMP-3 Inhibitor 1 - 5 mg,
MMP-3 Inhibitor 1 - 5mg , Ac-Arg-Cys-Gly-Val-Pro-Asp-NH2 Category/Application: Enzyme Substrates This item is non returnable
Echelon Biosciences Research Labs AS604850 (PI3-K gamma Inhibitor 2) 1 mg
5-(2,2-Difluoro-benzo[1,3]dioxol-5-ylmethylene)-thiazolidine-2,4-dione (AS604850) is an inhibitor of PI 3-K with an IC50 = 250 nM. AS604850 is selective for the -isoform (IC50: PI 3-K = 4.5 M, PI 3-K, PI 3-K > 20 M) and shows no notable activity against a wide array of protein kinases at 1 M.nn
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Solubility
nWater: insoluble, DMSO: 5 mg/mLnStorage
nStore dry between 2-8oC. Stock solutions should be stored frozen (-20oC).nReferences
n1) M. Camps et al. "Blockade of PI3Kg suppresses joint inflammation and damage in mouse models of rheumatoid arthritis" Nature Medicine, 2005, 11, 936-943.nnnn
Documents
nTechnical Data Sheet This item is non returnable