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Nickel affinity gel used for the purification of histidine-tagged proteins-6% beaded agarose. 50% suspension in 30% ethanol. Protein binding capacity is 15mg/ml
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Recombinant Human Thrombopoietin/TPO (His Flag) is a biotechnologically produced protein used in the field of hematopoiesis research Originating from human sources it primarily promotes the proliferation and differentiation of megakaryocyte progenitor cells via binding to the c-Mpl receptor activating JAK-STAT pathways In vitro its activity is often observed in the nanomolar to low micromolar range making it a valuable tool in studying thrombopoiesis It is commonly applied in cell culture models animal studies and drug screening assays providing insights into platelet production and related disorders Experimental concentrations typically depend on the specific research design
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Recombinant Mouse IL-17 (His Flag) is a cytokine used in biomedical research particularly in immunology and inflammation studies Originating from mouse models it plays a crucial role in mediating pro-inflammatory responses by signaling through the IL-17 receptor pathway influencing downstream effects like cytokine production and cell recruitment This protein is commonly tested at nanomolar to low micromolar concentrations for its in vitro activity It is frequently used in cell models to study inflammatory pathways and in animal studies to explore its role in diseases like autoimmune disorders Additionally it serves as an important tool in drug screening for evaluating potential therapeutic interventions targeting IL-17 mediated pathways Experimental concentrations typically depend on the specific research design
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