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Recombinant Human Thrombopoietin/TPO (His Flag) is a biotechnologically produced protein used in the field of hematopoiesis research Originating from human sources it primarily promotes the proliferation and differentiation of megakaryocyte progenitor cells via binding to the c-Mpl receptor activating JAK-STAT pathways In vitro its activity is often observed in the nanomolar to low micromolar range making it a valuable tool in studying thrombopoiesis It is commonly applied in cell culture models animal studies and drug screening assays providing insights into platelet production and related disorders Experimental concentrations typically depend on the specific research design
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Recombinant Swine GM-CSF (His Flag) is a specialized protein used in biomedical research primarily in the field of immunology and cell biology Originating from swine it functions by stimulating the growth and differentiation of hematopoietic cells especially targeting granulocyte-macrophage pathways Its mechanism involves binding to specific receptors on target cells facilitating a cascade of intracellular signals Commonly its in vitro activity is observed in the nanomolar to low micromolar range effective in various experimental setups It is typically applied in cell culture models and animal studies to investigate immune responses inflammation and potential therapeutic applications through drug screening Experimental concentrations typically depend on the specific research design allowing flexibility in use across different assays and studies
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Recombinant Mouse IL-10 (His Flag) is a cytokine involved in immunological research originating from the regulatory pathways of mice It plays a crucial role in modulating immune responses by inhibiting pro-inflammatory cytokines and promoting anti-inflammatory signaling This protein functions through the IL-10 receptor complex impacting JAK-STAT pathways to mediate its effects In vitro its activity is typically observed in the nanomolar to low micromolar range Commonly used in various cell models and animal studies this recombinant protein is instrumental in drug screening processes particularly in evaluating anti-inflammatory and immunosuppressive therapies Experimental concentrations typically depend on the specific research design and objectives making it a versatile tool in the investigation of immune system dynamics and therapeutic interventions
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Recombinant Mouse IL-17 (His Flag) is a cytokine used in biomedical research particularly in immunology and inflammation studies Originating from mouse models it plays a crucial role in mediating pro-inflammatory responses by signaling through the IL-17 receptor pathway influencing downstream effects like cytokine production and cell recruitment This protein is commonly tested at nanomolar to low micromolar concentrations for its in vitro activity It is frequently used in cell models to study inflammatory pathways and in animal studies to explore its role in diseases like autoimmune disorders Additionally it serves as an important tool in drug screening for evaluating potential therapeutic interventions targeting IL-17 mediated pathways Experimental concentrations typically depend on the specific research design
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Recombinant Human M-CSF/CSF1 (His Flag) is a crucial cytokine involved in the regulation of immune system functions Originating from human sources it plays a significant role in hematopoietic stem cell differentiation and macrophage lineage fate by binding to the CSF1 receptor Its mechanism of action involves the activation of signaling pathways that promote cell proliferation and survival This cytokine demonstrates potent activity in the nanomolar to low micromolar range when assessed in vitro It is commonly applied in cell models such as macrophage colony assays and utilized in animal studies to investigate immune responses and bone metabolism Additionally it serves an essential role in drug screening processes aimed at developing therapies for immune-related conditions Experimental concentrations typically depend on the specific research design
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Recombinant Mouse IL-19 (His Flag) is a protein used in biomedical research derived from mouse sources It belongs to the IL-10 cytokine family and plays a role in immune response modulation by activating specific signaling pathways such as the JAK-STAT pathway Its activity is commonly noted in the nanomolar to low micromolar range This recombinant protein is frequently utilized in in vitro studies involving cell lines contributing to our understanding of immune signaling and cytokine interactions In vivo it is useful in animal model studies aimed at exploring inflammation-related conditions Additionally it aids in drug screening applications allowing researchers to evaluate potential therapeutic agents targeting inflammatory pathways Experimental concentrations typically depend on the specific research design ensuring precision and relevance to the study s objectives
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Recombinant Mouse IL-13 (His Flag) is a cytokine used in biomedical research derived from mouse interleukin-13 and modified with His and Flag tags for purification and detection It plays a crucial role in immunological pathways primarily affecting the differentiation and activity of immune cells IL-13 is known to engage with the IL-13 receptor influencing various signaling cascades that regulate inflammation and immune responses In vitro this recombinant protein displays activity in the nanomolar to low micromolar range depending on the specific assay conditions It is widely applied in cell culture models to study immune modulation and is frequently used in animal models to investigate asthma and allergic responses Additionally it serves in drug screening processes aiming to find novel therapies targeting immune-related disorders Experimental concentrations of Recombinant Mouse IL-13 typically depend on the specific research design and objectives of the study
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Recombinant Mouse M-CSF/CSF1 (His Flag) is a critical cytokine involved in the regulation of macrophage lineage cells originating from murine sources It functions by binding to its receptor CSF1R on the cell surface triggering downstream signaling pathways crucial for survival proliferation and differentiation of macrophages In vitro activities are often observed in the nanomolar to low micromolar range making it a valuable tool in research It is widely used in cell models animal studies and drug screening to explore macrophage-related functions and therapeutic interventions Experimental concentrations typically depend on the specific research design
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Flag-tag Protein IP Assay Kit Agarose Gel is an immunoprecipitation assay kit targeting Flag-tagged proteins It is designed to enable the specific isolation and characterization of Flag-tagged proteins or protein complexes from various biological samples using immobilized anti-DYKDDDDK (Flag) affinity agarose gel The kit functions by affinity-based recognition and binding of the Flag-tag epitope (DYKDDDDK) on recombinant proteins via immobilized antibodies Based on its utility Flag-tag Protein IP Assay Kit Agarose Gel offers research applications in immunoprecipitation (IP) and co-immunoprecipitation (Co-IP) assays for isolation or analysis of Flag-labeled proteins and their interacting complexes
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