Protein Resins
G-Biosciences Recombinant Protein A/G
Recombinant Protein A/G contains four Fc-binding domains from Protein A and two from Protein G but lacks the albumin binding sites.
Sigma Aldrich Fine Chemicals Biosciences Gammabind Plus SepharoseR
GammaBind Plus Sepharose(R) is used for lab-scale affinity purification of IgG from a large variety of species and has better binding to rat and mouse IgG subclasses compared to GammaBind Sepharose.GammaBind Plus Sepharose(R) is GammaBind G Type 3 covalently immobilized to Sepharose(R) CL-6B by malimide linkage. GammaBind G Type 3 a recombinant form of streptococcal protein G binds to the Fc region of IgG from a variety of mammalian species. GammaBind Plus Sepharose(R) may be used to analyze and purify classes subclasses and fragments of immunoglobulins from any biological fluid or cell culture medium. Since only the Fc region is involved in binding the Fab region is still available for binding antigen.
Sigma Aldrich Fine Chemicals Biosciences HiTrapR MabSelectTM PrismA
These HiTrap columns are prepacked with MabSelect PrismA protein A chromatography resin. This affinity resin in the packed column has been improved with an optimized high-flow agarose base matrix and a genetically engineered protein ligand allowing efficient cleaning between monoclonal antibody purification runs. This allows future demands in monoclonal antibody purification to be met including processing of many bispecific antibodies..nbspEnhanced dynamic binding capacity compared with other protein A resins..nbspExcellent alkaline stability enables efficient cleaning and sanitization using 0.5-1.0 M NaOH..nbspConvenient HiTrap format for easy connection to a syringe peristaltic pump or chromatography systems such as an ÄKTA system for convenient process optimization.The enhanced alkaline stability of MabSelect PrismA also provides opportunities for more robust mAb purification using periodic counter-current chromatography. The possibility for cleaning using 1 M NaOH increases bi
Sigma Aldrich Fine Chemicals Biosciences HiTrapR MabSelect SuReTM C
HiTrap(R) MabSelect(TM) SuRe(TM) columns are prepacked with MabSelect(TM) SuRe a BioProcess medium for purification of monoclonal antibodies from large sample volumes. The novel alkali-tolerant recombinant Protein A ligand allow cleaning-in-place (CIP).HiTrap(R) MabSelect(TM) columns are prepacked with MabSelect(TM) a bioprocess medium for capuring of Mabs from large sample volumes.
Sigma Aldrich Fine Chemicals Biosciences HiTrapR MabSelectTM Cytiva
HiTrap(R) MabSelect(TM) columns are prepacked with MabSelect a Bioprocess medium for capuring of Mabs from large sample volumes.
Sigma Aldrich Fine Chemicals Biosciences HiScreenTM MabSelect SuReT
HiScreen(TM) MabSelect(TM) SuRe(TM) LX is prepacked with MabSelect(TM) SuRe(TM) LX and is part of the process development platform available from Cytiva. The columns are an excellent choice for method optimization and parameter screening for capture of monoclonal antibodies when a high binding capacity is needed.
Sigma Aldrich Fine Chemicals Biosciences HiTrapR MabSelect SuReTM L
.nbspNovel alkali-tolerant rProtein A ligand withstands rigorous CIP and sanitization procedures with 0.1 to 0.5 M NaOH..nbspReduces the risk of product contamination and carryover.nbspImproves performance and reduces overall costs.nbspHigh dynamic binding capacity (DBC) for high titer cultures reduces process time and amount of medium used.nbspGeneric elution profile for different monoclonal antibodies enables platform approach to purification.nbspHigh-flow agarose matrix allows the processing of large feed volumes
Sigma Aldrich Fine Chemicals Biosciences MAbtrapR Kit Cytiva 17 112
MAbTrap(R) is an affinity chromatography kit with everything required for small-scale IgG purification from ascites fluid serum and cell culture supernatants.
Sigma Aldrich Fine Chemicals Biosciences Protein G from Streptococc5MG
Genetically engineered truncated protein G retains affinity for IgG but lacks albumin- and fab- binding sites and membrane-binding regions.
Sigma Aldrich Fine Chemicals Biosciences YopH Protein active 10 1
Product Source recombinant Yersinia full length YopH expressed in E. coli
Sigma Aldrich Fine Chemicals Biosciences Protein G Mag SepharoseR C
Protein G Mag Sepharose(R) are magnetic beads designed to simplify enrichment of target proteins by immunoprecipitation applications. Based on Sepharose(R) with Protein G as ligand. Protein G has high affinity for the fc region of IgG antibodies.
Sigma Aldrich Fine Chemicals Biosciences MabSelectTM PrismA Cytiva
MabSelect PrismA affinity chromatography resin has been improved with an optimized high-flow agarose base matrix and a genetically engineered protein A-derived ligand. This allows future demands in mAb purification to be met including processing of many bispecific antibodies.Enhanced dynamic binding capacity allows high mass throughput of processed mAb per resin volume unit.Excellent alkaline stability enables efficient cleaning and sanitization using 0.5-1.0 M NaOH for improved process economy bioburden control and robustness.The enhanced alkaline stability of MabSelect PrismA also provides opportunities for more robust mAb purification using periodic counter-current chromatography. The possibility for cleaning using 1 M NaOH increases bioburden control for continuous processes which can be exposed to days or weeks of feed harvest.
Sigma Aldrich Fine Chemicals Biosciences MabSelectTM SuReTM Cytiva
MabSelect(TM) SuRe(TM) is a protein A affinity medium for capturing MAbs at process scale. MabSelect(TM) SuRe(TM) has an alkali-tolerant rProtein A ligand that allows the use of rigorous and cost-effective CIP and sanitization protocols based on 0.1 to 0.5 M NaOH. Further the ligand is protease stable leading to lower ligand leakage.MabSelect(TM) SuRe(TM) is a member of the MabSelect(TM) family of affinity chromatography media for the capture of monoclonal antibodies (MAbs) at process scale. MabSelect(TM) SuRe(TM) shares features and benefits of MabSelect(TM) such as a rigid high-flow agarose matrix that ensures excellent pressure/flow properties low non-specific binding that leads to low impurity levels in the eluate pool and an oriented ligand coupling for optimal binding capacity. In addition MabSelect(TM) SuRe(TM) features an alkali-tolerant rProtein A ligand. This ligand provides greater stability than conventional protein A-based media in the alkaline conditions used in clea
Sigma Aldrich Fine Chemicals Biosciences MabSelect SuReTM LX Cytiva
MabSelect(TM) SuRe(TM) LX is a protein A affinity medium with very high dynamic binding capacity at extended residence times and is developed for high titer antibody processes. Alkali tolerance high capacity and low ligand leakage in combination with the rigid base matric makes MabSelect(TM) SuRe(TM) LX highly suitable for purification of monoclonal anitbodies for clinical applications.MabSelect(TM) SuRe(TM) LX is a member of the MabSelect(TM) family of affinity chromatography media for the capture of monoclonal antibodies (MAbs) at process scale. MabSelect(TM) SuRe(TM) LX shares features and benefits of MabSelect(TM) and MabSelect(TM) SuRe(TM) such as a rigid high-flow agarose matrix that ensures excellent pressure/flow properties low non-specific binding that leads to low impurity levels in the eluate pool and an oriented ligand coupling for optimal binding capacity. It also features the same alkali-tolerant rProtein A ligand as MabSelect(TM) SuRe. This ligand provides greater st
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