Non-Mammalian cDNA
Cayman Chemical GDF11humn recombInt 10ug
An insect pheromone used in pesticides activates antennal basiconic Or7a receptors in Drosophila produced by honey bees to communicate information about food sources
Cayman Chemical 8 12-Iso-IPF2a-VI 10ug
The most abundant isoprostane product formed during lipid peroxidation; detected after CCl4-induced oxidative damage to hepatic tissue and has been found elevated in the urine, blood, and CSF of patients with Alzheimer’s disease
Cayman Chemical SrchumnrecombInt 10ug
Source: Active recombinant human N-terminal GST-tagged Src expressed in insect cells • Amino acids: 1-536 • MW: 86 kDa
Cayman Chemical 7-epI MaresIn 1 10ug
The inactive 7(S) epimer of Maresin 1; useful as an experimental negative control
Cayman Chemical 14S 15R-EET methyl ester 10ug
A cytochrome P450 metabolite of arachidonic acid; binds to isolated guinea pig monocytes (Ki = 612.5 nM in a radioligand binding assay); induces dilation of precontracted isolated canine epicardial arterioles (EC50 = 4 pM) and denuded porcine subepicardial arterioles (EC50 = 3 pM)
Cayman Chemical ResolvIn E2 10ug
An SPM; inhibits increases in inflammatory exudate neutrophil infiltration in a zymosan A-induced mouse model of peritonitis; hepatic levels are increased in mice fed normal chow, as well as in a mouse model of high-fat diet-induced NAFLD, by dietary supplementation with EPA; plasma levels are increased by dietary supplementation with fish oil containing ω-3 PUFAs in patients with chronic kidney disease or peripheral artery disease
Cayman Chemical XestospongIn C 10UG
An inositol-1,4,5-trisphosphate receptor antagonist; completely blocks the increase in intracellular calcium in vascular smooth muscle cells at a concentration of 25 µM
Cayman Chemical 17 RRSolvIn D1 methyl Ste 10UG
A methyl ester version of 17(R)-RvD1 which may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties
Cayman Chemical 13 14dIhydro15ketotetrno 10ug
A major urinary metabolite of PGE2 that is excreted in guinea pig urine at a concentration range of 1.34-2.74
Cayman Chemical JAK3 JH2 DomaInhumnrecom 10ug
Source: Active recombinant human C-terminal AVI- and His-tagged JAK3 JH2 domain expressed in insect cells (sf9) • Amino acids: 511-790 • MW: 34 kDa
Cayman Chemical 17 R-ResolvIn D3 10UG
An aspirin-triggered epimer of resolvin D3; has been found in mouse inflammatory exudates; reduces transmigration of neutrophils into the peritoneal cavity, as well as decreases the levels of IL-6 and increases the levels of IL-10 in inflammatory exudate in a mouse model of zymosan-induced peritonitis at 10 ng/animal; activates GPR32 in a β-arrestin reporter assay and increases phagocytosis to a greater degree in CHO cells overexpressing GPR32 compared to mock-transfected cells; increases phagocytosis of etoposide-generated tumor cell debris by monocyte-derived macrophages in H460 human lung carcinoma cells in a concentration-dependent manner; inhibits tumor growth in a mouse model of Lewis lung carcinoma at 0.6 UG/kg per day
Cayman Chemical LeukotrIen B4-d5 10ug
An internal standard for the quantification of LTB4 by GC- or LC-MS
Cayman Chemical LPA2 Antagonist 1, Purity: ≥98%, CAS: 1017606-66-4, 10 mg
An LPA2 antagonist (IC50 = 17 nM); selective for LPA2 over LPA1 and LPA3 (IC50s = >50 μM); inhibits HGF-induced phosphorylation of ERK and proliferation of HCT116 colon cancer cells
Cayman Chemical MaresIn 2-d5 10ug
An internal standard for the quantification of MaR2 by GC- or LC-MS
Cayman Chemical MRTK EXrAClular DomaInh 10ug
Source: Active recombinant human N-terminal GST-tagged MERTK expressed in insect cells • Amino acids: 578-872 • MW: 60 kDa