Toxins
Toxin Technologies Inc HIGHLY PURIFIED SEB 1MG
SEB; Highly Purified; 1mg; Intended for laboratory and research purposes only; Not intended for human or veterinary drug use
Apexbio Technology LLC Berberine Sulfate,20mgCAS# 633-66-9
Extracted from Berberisthunbergiicv.atropurpurea;Store the product in sealed, cool and dry condition. Other sizes are also available. Please inqury us for quote.
Apexbio Technology LLC Bufalin 465-21-4 20mg
Bufalin (CAS 465-21-4) is a cardiotonic steroid compound originally derived from the venom of the Chinese toad It exerts its biological effects by modulating intracellular signaling pathways notably by inducing apoptosis and promoting cell differentiation in human monocytic U-937 cells Mechanistic studies suggest that Bufalin activates the AP-1 transcription factor via a mitogen-mediated pathway contributing to its observed effects on cell fate Due to these properties Bufalin is employed in biomedical research to investigate mechanisms of apoptosis cell differentiation and the role of steroidal compounds in cellular signaling pathways
Apexbio Technology LLC Pertussis Toxin(Synonyms: PTX, Pertussigen, Pertussis toxin protein, Islet-activating protein, Pertussis toxoid), 50ug, CAS: 70323-44-3.
Pertussis toxin (CAS 70323-44-3) is an AB5-type protein exotoxin produced by Bordetella pertussis the bacterium responsible for whooping cough Mechanistically pertussis toxin modulates host immune responses primarily via a cAMP-dependent pathway as demonstrated by its actions on human monocyte-derived dendritic cells influencing their maturation and cytokine production In animal models treatment reduces norepinephrine-induced contractions in rat mesenteric resistance arteries without notable effects on mouse tracheal contractility Pertussis toxin serves as a research tool in immunological studies and is central to acellular pertussis vaccines designed to limit disease transmission and severity across susceptible populations
Apexbio Technology LLC SAIKOSAPONIN-A-20MG
Saikosaponin A (CAS No 20736-09-8) is a triterpenoid saponin primarily derived from the roots of the Bupleurum plant widely studied in the field of biomedical research for its diverse pharmacological properties It is known to modulate various signaling pathways including the MAPK and NF- B pathways which are crucial in inflammation and cell growth regulation In vitro Saikosaponin A exhibits activity in the nanomolar to low micromolar range indicating potent bioactivity It is frequently employed in research involving various cancer cell lines and inflammatory models due to its potential anti-cancer and anti-inflammatory effects Additionally it is used in animal studies and drug screening programs focusing on liver protection and immune modulation Experimental concentrations typically depend on the specific research design allowing for application in diverse experimental settings
Apexbio Technology LLC Matrine(Synonyms: Sophocarpidine, Matridin, (-)-Matrine, α-Matrine, (−)-α-Matrine, L-Matrine, Kushenin), 100mg, CAS: 519-02-8.
Matrine (CAS 519-02-8) is an alkaloid derived from plants in the Sophora genus with demonstrated anticancer and anti-inflammatory activities It functions in part through agonism of kappa-opioid and possibly other receptors Matrine inhibits the MNK45 gastric cancer cell line proliferation (IC50 540 g/ml MTT assay) by modifying protein expression profiles (e g NF- B XIAP CIAP p-ERK) In vitro matrine induces apoptosis in NSCLC cells through ROS generation caspase activation and p38 pathway modulation Animal studies suggest therapeutic roles in cardiac injury and sepsis-related lung inflammation
Apexbio Technology LLC L-Arabitol 7643-75-6 500mg
L-Arabitol (CAS 7643-75-6) is a naturally occurring pentitol detected in various plant and animal sources Functioning as a metabolic product of dietary pentose sugars L-Arabitol is increasingly employed as a dietary biomarker for food intake assessment in nutritional studies Altered plasma or urinary concentrations of L-Arabitol have been reported in certain pathological conditions including Alzheimer s disease and phosphoisomerase deficiencies indicating its potential utility in monitoring metabolic disruptions or aiding early disease diagnosis Consequently L-Arabitol is widely utilized in biomedical research as a non-invasive indicator of metabolic or pathological status
Apexbio Technology LLC Xanthohumol,10mg CAS# 6754-58-1
Valosin-containing protein (VCP) inhibitor. Binds to the N domain of VCP, suppressing function and impairing autophagosome maturation. Inhibits growth of a wide variety of human cancer cell lines by inhibiting proliferation and inducing apoptosis. Other sizes are also available. Please inqury us for quote.
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