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Cytokines and reagents that can be added to cell cultures and used to investigate a variety of cell pathways and metabolic processes. Products also include a variety of kits, immunoassays, arrays, and staining products for use in cytokine analysis experiments.
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Interleukin 6 (IL-6) is secreted by T cells and macrophages and acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. Some of its functions include the stimulation of the immune response during infection induction of fever in autoimmune infectious and non-infectious diseases the stimulation of acute phase reactions differentiation of T cells proliferation and differentiation of B-cells the development of blood cells as well as the activation of osteoclasts and osteoporosis and the secretion of vascular endothelium growth factor (VEfG) to increase blood vessel growth and vascular permeability in inflammation. It is important for a short-term defense against infection injury and inflammation however dysregulation of IL-6 results in disease.IL-6 is important in the study of diseases such as diabetes lupus multiple myeloma rheumatoid arthritis and some cancers such as prostate and pancreatic cancer. Conversely deficiency of IL-6 can have an effect on immune
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Recombinant Interleukin-2 human (hIL-2) is produced in E. coli and purified by standard chromatographic techniques. SOLUTIONon in PBS and 1 mg/ml BSA filtered through a 0.2 mum pore size membrane.
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Interleukin-2 (IL-2) is an helical cytokine belonging to T-helper cell type 1. It has a molecular weight of 15kDa. The IL2 gene is mapped to human chromosome 4q27. IL-2 is originally called as T cell growth factor.
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Interleukin-3 is a hematopoietic growth factor which stimulates basophil development and triggers histamine IL-4 and IL-6 release. It improves monocyte and macrophage activation and phagocytosis enhances the secretory function of eosinophils. Interleukin-3 promotes endothelial cell proliferation and migration.
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