Protein Modification Reagents
ILEX LIFE SCIENCES LLC Cellendes 3-D Life PVA-PEG Hydrogel SG Ready-To-Design Kit (1 Kit)
3-D Life is the most flexible system for biomimetic hydrogel design. It uses two polymers that form a hydrogel by covalent crosslinking at ambient temperature. The chemical reaction is non-toxic to cells and occurs rapidly, preventing cell settlement before the gel is formed. 3-D Life PVA-PEG Hydrogel SG Kit provides reagents for setting up slow gelling, cell-compatible hydrogels for 3D cell cultures. Components are mixed at physiological pH 7.2 for optimal cell compatibility. Slow gelation allows enough time to manipulate the solution before onset of gel formation. Peptides (e.g. 3-D Life RGD Peptide, Cat. No. 09-P-001) can be covalently attached to a portion of the SH-reactive groups of SG-PVA to provide a cell-adhesive matrix. One kit allows formation of up to 2 ml hydrogel depending on gel stiffness. Manufactured in Germany by Cellendes GmbH.
Enzo Life Sciences Caspase-1 (human), (recombinant) (5000 U)
Highly active caspase essential for apoptosis. Alternative name: Interleukin 1 beta converting enzyme, IL-1 beta converting enzyme, ICE. MW: ~20 + 10kDa. Concentration: 100 U/µl. Purity: ≥90% (SDS-PAGE). Formulation: Liquid. In 50mM HEPES, pH 7.4, containing 100mM sodium chloride, 0.5% CHAPS, 1mM EDTA, 10% glycerol and 10mM DTT. Source: Produced in E. coli. cDNA encodes residues identical to Asn120-His404 (C-terminus) at Genbank Accession No. M87507, except for an Asp381 to Glu change, introduced to stabilize the enzyme against autoproteolysis.
Enzo Life Sciences DTT (5g). CAS: 3483-12-3
Cell permeable protective agent for SH groups, maintaining monothiols completely in the reduced state and of reducing disulfides quantitatively. ER-stress inducer. Alternative name: 1,4-Dithio-DL-threitol, DL-Dithiothreitol, Cleland's Reagent. Purity: ≥98% (Assay by Iodometric Titration). Solubility: Soluble in water, 100% ethanol, acetone or ethyl acetate. Long Term Storage: +4°C.
Enzo Life Sciences MMP-2 (catalytic domain) (human), (recombinant) (10 µg)
Alternative name: Matrix metalloproteinase 2. Gelatinase A. 72 kDa Type IV collagenase. MW:~40kDa. Purity: ≥90% (SDS-PAGE). Formulation: Liquid In 50mM TRIS-HCl, pH 7.5, containing 300mM NaCl, 5mM CaCl2, 20µM ZnCl2, 0.05% Brij-35 and 20% glycerol. Source: Produced in yeast. Active recombinant matrix metalloproteinase-2 (MMP-2, gelatinase A, 72kDa type IV collagenase) cloned from human cDNA The enzyme consists of residues Tyr110-Asp452, which comprises the catalytic/fibronectin domain of human MMP-2, with a C-terminal purification tag. Use/Stability: The enzyme is stable on ice for at least several hours. However, it is recommended that thawing and dilution of the enzyme be done within as short a time as possible before start of the assay. After initial defrost, aliquot product into individual tubes and refreeze at -70°C. Avoid repeated freeze/defrost cycles.
Enzo Life Sciences D-myo-Inositol 1,4,5-trisphosphate . hexapotassium salt (5mg). CAS: 103476-24-0
Product of phosphatidylinositol phospholipid hydrolysis. Causes release of calcium from intracellular stores. Alternative name: Ins(1,4,5)P3 . 6K, IP3. Purity: ≥98% (TLC). Appearance: White to off-white powder. Solubility: Soluble in water. Long Term Storage: -20°C.
Enzo Life Sciences Gefitinib-based PROTAC 3 (1mg). CAS: 2230821-27-7
Gefitinib-based PROTAC 3 is targeting on EGFR, consisting of Gefitinib as the warhead linked to VHL-recruiting ligand. Purity: ≥99%. Solubility: Soluble in DMSO (75 mg/mL). Insoluble in water. Long Term Storage: -20°C.
Enzo Life Sciences DTT (10g). CAS: 3483-12-3
Cell permeable protective agent for SH groups, maintaining monothiols completely in the reduced state and of reducing disulfides quantitatively. ER-stress inducer. Alternative name: 1,4-Dithio-DL-threitol, DL-Dithiothreitol, Cleland's Reagent. Purity: ≥98% (Assay by Iodometric Titration). Appearance: White to off-white solid. Solubility: Soluble in water, 100% ethanol, acetone or ethyl acetate. Long Term Storage: +4°C.
Enzo Life Sciences Caspase-6 (human), (recombinant) (5000 U)
Alternative name: Mch2. Concentration: 100 U/µl. Purity: ≥80% (SDS-PAGE). Formulation: Liquid. In 50mM HEPES, pH 7.4, containing 100mM sodium chloride, 0.5% CHAPS, 1mM EDTA, 10% glycerol and 10mM DTT. Source: Produced in E. coli. Long Term Storage: -80°C.
Enzo Life Sciences D-myo-Inositol 1,4,5-trisphosphate . hexapotassium salt (1mg). CAS: 103476-24-0
Product of phosphatidylinositol phospholipid hydrolysis. Causes release of calcium from intracellular stores. Alternative name: Ins(1,4,5)P3 . 6K, IP3. Purity: ≥98% (TLC). Appearance: White to off-white powder. Solubility: Soluble in water. Long Term Storage: -20°C.
Discovery Life Sciences Gastric Cancer DTC
DTC Dissociated Tumor and Tissue Cells start as fresh solid tumor tissue collected during surgery are enzymatically and mechanically dissociated into single cells and are delivered as viably cryopreserved cells for functional assays cell culture and single cell genomics
Discovery Life Sciences Gastric Cancer MSI H DTC
DTC Dissociated Tumor and Tissue Cells start as fresh solid tumor tissue collected during surgery are enzymatically and mechanically dissociated into single cells and are delivered as viably cryopreserved cells for functional assays cell culture and single cell genomics
Discovery Life Sciences Gastric Cancer MSS DTC
DTC Dissociated Tumor and Tissue Cells start as fresh solid tumor tissue collected during surgery are enzymatically and mechanically dissociated into single cells and are delivered as viably cryopreserved cells for functional assays cell culture and single cell genomics
