PTMScan™ technology employs a proprietary methodology for post-translationally modified peptide enrichment by immunoprecipitation using a specific agarose bead-conjugated antibody in conjunction with liquid chromatography-tandem mass spectrometry (LC-MS/MS) for quantitative profiling of O-GlcNAc modified sites in cellular proteins. The workflow provides a global, unbiased overview of O-GlcNAc modifications across cell and tissue samples of any species, enabling researchers to isolate, identify, and quantify large numbers of modified peptides.
- Enables quantitative profiling of O-GlcNAc [GlcNAc-S/T] motifs.
- Utilizes high-affinity, agarose bead-conjugated antibodies.
- Compatible with diverse cell and tissue sample types.
- Designed for 10 assays.
- Validated for use in proteomics research applications.
- Supplied with immunoaffinity beads and 10X IAP buffer.