Crosslinking Reagents
Thermo Scientific™ Pierce™ Controlled Protein-Protein Crosslinking Kit
Chemically conjugate any two purified proteins (antibodies, enzymes, carriers, etc.) using sulfo-SMCC crosslinker, a complete kit with modification reagents and buffers.
Thermo Scientific™ Sulfo-SMCC (sulfosuccinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate), No-Weigh™ Format
Crosslink amines to sulfhydryls with this mid-length, water-soluble crosslinker made of NHS-ester and maleimide groups at ends of a cyclohexane-containing, 8-atom spacer arm.
Thermo Scientific™ Pierce™ DSG, No-Weigh™ Format
Thermo Scientific™ Pierce™ DSG is water-insoluble, homo-bifunctional N-hydroxysuccinimide ester (NHS-ester) crosslinker often used for conjugating radiolabeled ligands to cell-surface receptors.
Broadpharm DBCO-Sulfo-NHS ester, 1400191-52-7, MFCD22572669, 25mg
Formula: C25H21N2NaO8S, Purity: 97%, MW: 532.5, DBCO-Sulfo-NHS ester is a water-soluble sulfocated reagent containing DBCO moiety. It can be used for simple and efficient labeling of antibodies, proteins and any other primary amine-bearing macromolecules with DBCO moiety in 100% aqueous buffers.
Medchemexpress LLC Octanedioic acid, 1,8-bis(2,5-dioxo-3-sulfo-1-pyrrolidinyl) ester | 82436-77-9 | 98.0% | 528.47 g·mol⁻¹ | C16H20N2O14S2 | 50 MG
BS3 Crosslinker is a water-soluble, non-cleavable homobifunctional crosslinker that reacts with primary amines to form stable amide bonds. It contains sulfo-NHS ester groups that enable efficient conjugation in aqueous buffers, making it suitable for protein crosslinking and antibody-drug conjugate synthesis in research applications.
- Water soluble and membrane impermeable, enabling reactions in aqueous buffers.
- Reacts with primary amines via NHS-ester chemistry for efficient conjugation.
- Forms stable, non-cleavable amide bonds for durable linkages.
- Compatible with antibody-drug conjugate (ADC) and protein crosslinking workflows.
- Supplied with defined purity and characterized molecular weight for reproducibility.
- Available in small lab-friendly pack sizes for research use.
Medchemexpress LLC Octanedioic acid, 1,8-bis(2,5-dioxo-3-sulfo-1-pyrrolidinyl) ester | 82436-77-9 | 98.0% | 528.47 g/mol | C16H20N2O14S2 | 10 MG
BS3 Crosslinker is a water-soluble, non-cleavable, amine-reactive homobifunctional crosslinker (sulfo-NHS ester) designed for bioconjugation and protein crosslinking in aqueous systems. It selectively reacts with primary amines to form stable amide bonds and is commonly used for protein structural studies, surface crosslinking, and as a linker in antibody-drug conjugate research.
- Water-soluble sulfo-NHS ester for use in aqueous buffers.
- Reacts with primary amines to form stable amide bonds.
- Non-cleavable linker for stable, long-lived conjugates.
- Membrane-impermeable, suitable for surface and extracellular crosslinking.
- Useful for bioconjugation, protein structural analysis, and linker development.
Medchemexpress LLC Sulfo-cyanine5 DBCO | 981.27 | C53H57KN4O8S2 | 10 MG
Sulfo-Cyanine5 DBCO is a water-soluble near-infrared fluorescent dye bearing a dibenzocyclooctyne (DBCO) reactive group for copper-free click chemistry. It is intended for bioorthogonal labeling of azide-containing biomolecules and fluorescence imaging in aqueous media.
- Near-infrared fluorescent dye (Ex/Em 646/670 nm).
- DBCO reactive handle enables strain-promoted alkyne-azide cycloaddition (SPAAC).
- Water-soluble sulfonated cyanine core for labeling in aqueous buffers.
- Suitable for conjugation to proteins, peptides, and nucleic acids.
- Store sealed, away from moisture and light; in solvent store at -80°C (6 months) or -20°C (1 month).
Cell Signaling Technology Human Reactive Inflammatory Cytokine Antibody Sampler Kit, Unconjugated, 1 Kit
The Human Reactive Inflammatory Cytokine Antibody Sampler Kit offers an economical solution for detecting the expression of various cytokines associated with inflammatory responses. This kit includes a comprehensive selection of primary antibodies to facilitate the study of cytokine profiles in human samples via western blot analysis. It provides sufficient antibody volume to perform two western blot experiments for each target.
- Includes antibodies for detection of IL-1α, IL-1β, IL-2, IL-4, IL-6, IL-8, IL-10, IFN-γ, and TNF-α
- Supplied with HRP-linked anti-rabbit IgG secondary antibody for chemiluminescent detection
- Antibodies are provided in optimized storage buffer with glycerol and BSA for stability
- Format: 1 kit containing 20 μL of each primary antibody and 100 μL of secondary antibody