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UV Crosslinkers

Instruments allowing for quick, safe, and efficient sample exposure to a controlled amount of UV radiation. Used to modify the structures of nucleic acids, proteins and microorganisms; in linking nucleic acids to membranes for blotting procedures; etc.

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Medchemexpress LLC 1,4-diazoniabicyclo[2.2.2]octane, 1,4-bis[4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxobutyl]-dibromide | 1374647-94-5 | 99.0% | 5 MG
SDP

DC4 Crosslinker is a mass-spectrometry-cleavable crosslinking reagent used to link proximal amino acid residues for crosslinking-mass spectrometry (XL-MS). It is designed for CID cleavage to produce characteristic fragment ions for mapping protein-protein interactions and generating distance restraints for structural modeling.

  • Designed for collision-induced dissociation (CID) cleavage
  • Contains two intrinsic positive charges to aid fragmentation
  • High purity suitable for proteomics workflows
  • Soluble in DMSO at high concentration
  • Available in small vials for method development

ENCOMPASS_PREFERRED
2

Proteochem Inc DSG CROSSLINKER 1GM

  • Homobifunctional crosslinker for protein modification.
  • Membrane-permeable for enhanced cell interaction.
  • Amines-reactive NHS esters form stable amide bonds.
  • 5-atom spacer arm measuring 7.7 Å for flexibility in binding.
  • Chemical formula: C13 H14 N2 O8.
  • Molecular weight: 326.26 g/mol.
  • CAS Number: 79642-50-5.
  • Purity ≥ 97% as determined by quantitative NMR.
  • Solubility in DMSO or DMF is required.
  • Effective in ChIP assays and Region Capture Micro-C protocols.
  • Optimal reaction pH range of 7 to 9 for primary amines.

ENCOMPASS_PREFERRED