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Chemical reagents and products designed to conduct fluorescent in situ hybridizations, a technique used to bind fluorescent probes to specific nucleic acids. Products may be available as kits.
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A TTR kinetic stabilizer selectively binds to wild-type TTR and TTRV122I with negative cooperativity (Kd1s 4.8 and 6.2 nM respectively Kd2s 314 and 139 nM respectively) over COX-1 COX-2 and the thyroid hormone nuclear receptor (IC50s >10 UM for all) inhibits pH-induced amyloidogenesis of wild-type TTR and TTRV122I indicating tetramer stabilization stabilizes TTRV122I in serum isolated from patients with familial amyloid cardiomyopathy at 10 UM
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Contains a collection of small, drug-like molecules that inhibit or antagonize epigenetic readers, writers, and erasers each packaged as a 1 mg sample size for ease of preclinical target validation during early stages of drug discovery
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More