FuGENE SI is a novel, multicomponent transfection reagent for high efficiency, and low toxicity delivery of siRNA, miRNA, and other short RNAs into common and difficult-to-transfect eukaryotic cells. FuGENE SI enables researchers to obtain superior gene silencing and knockdown efficiencies while utilizing lower amounts of siRNAs. The simple, easy-to-use protocol with minimal optimization allows users to free up valuable lab time. Compatible with all commercially available and lab-synthesized siRNAs and miRNAs. See the Unseen with FuGENE SI.