Imidazoles
Selleck Chemical LLC Mizolastine S2107-50mg
Mizolastine (SL 850324) is a histamine H1-receptor antagonist with IC50 of 47 nM used in the treatment of hay fever (seasonal allergic rhinitis) hives and other allergic reactions
Selleck Chemical LLC ML240 | 1346527-98-7 | 396.4 g/mol | 5MG
ML240 | 1346527-98-7 | 396.4 g/mol | 5MG
Selleck Chemical LLC 2-Picolinic acid methyl ester
2-Picolinic acid methyl ester (Methyl picolinate 2-Pyridinecarboxylic acid methyl ester Methyl pyridine-2-carboxylate) is used as pharmaceutical intermediate
Selleck Chemical LLC CA-5f
CA-5f is a potent late-stage macroautophagy/autophagy inhibitor via inhibiting autophagosome-lysosome fusion
Selleck Chemical LLC Azathioprine-50mg
Azathioprine(BW 57-322) is an immunosuppressive drug, inhibiting purine synthesis and GTP-binding protein Rac1 activation, used in the treatment of organ transplantation and autoimmune diseases.
Selleck Chemical LLC VS-5584
VS-5584 (SB2343) is a potent and selective dual PI3K/mTOR inhibitor for mTOR PI3K / / / with IC50 of 3 4 nM and 2 6-21 nM respectively Phase 1
Selleck Chemical LLC RAF265 (CHIR-265) S2161-25mg
RAF265 (CHIR-265) is a potent selective inhibitor of C-Raf/B-Raf/B-Raf V600E with IC50 of 3-60 nM and exhibits potent inhibition on VEGFR2 phosphorylation with EC50 of 30 nM in cell-free assays RAF265 (CHIR-265) induces cell cycle arrest and apoptosis Phase 2
Selleck Chemical LLC CTEP (RO4956371) S2861-5mg
CTEP (RO4956371) is a novel long-acting orally bioavailable allosteric antagonist of mGlu5 receptor with IC50 of 2 2 nM shows 1000-fold selectivity over other mGlu receptors
Selleck Chemical LLC L-5-Methyltetrahydrofolate calcium S5264-1g
Calcium L-5-methyltetrahydrofolate (L-5-MTHF-Ca) is a synthetic derivative of folic acid the predominant naturally occurring form of folate
Selleck Chemical LLC Dabigatran (BIBR-1048) etexilate S2154-5mg
Dabigatran Etexilate (BIBR-1048) is the prodrug of dabigatran a potent nonpeptidic small molecule that specifically and reversibly inhibits both free and clot-bound thrombin by binding to the active site of the thrombin molecule
Selleck Chemical LLC IEM 1754 2HBr S2860-10mg
IEM 1754 2HBr is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 M
Selleck Chemical LLC BAY 1436032
BAY-1436032 is a highly selective potent and orally available inhibitor of mutant Isocitrate Dehydrogenase 1 (mIDH1) It is a double-digit nanomolar and selective pan-inhibitor of the enzymatic activity of various IDH1-R132X mutants in vitro and displays potent inhibition of 2-HG release (nanomolar range) in patient derived and engineered cell lines expressing different IDH1 mutants
Selleck Chemical LLC BIA 10-2474
BIA 10-2474 is a novel fatty acid amide hydrolase (FAAH) inhibitor with a potent inhibitory effect upon FAAH and prolonged action in vivo