Monocarboxylic acids and derivatives
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Medchemexpress LLC Mal-NH-ethyl-SS-propionic acid | 2128735-24-8 | MFCD31536759 | 99.9% | 332.40 | C12H16N2O5S2 | 25 MG
Mal-NH-ethyl-SS-propionic acid is a cleavable antibody-drug conjugate (ADC) linker designed for thiol conjugation and reductive release of payloads in target cells. It contains a maleimide reactive group, a disulfide cleavable spacer, and a terminal propionic acid, and is supplied as a solid for research use only.
- Cleavable disulfide spacer enables reductive release of payloads inside cells.
- Maleimide functional group reacts selectively with thiol groups for conjugation.
- Terminal carboxylic acid provides a handle for further functionalization.
- High purity suitable for research applications.
- Available in multiple small-scale pack sizes for lab use.
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Medchemexpress LLC Mal-NH-ethyl-SS-propionic acid | 2128735-24-8 | MFCD31536759 | 99.9% | 332.40 g/mol | C12H16N2O5S2 | 50 MG
Mal-NH-ethyl-SS-propionic acid is a cleavable antibody-drug conjugate (ADC) linker containing a maleimide reactive group and a disulfide-containing spacer that enables conjugation to thiol groups and reductive payload release under intracellular reducing conditions.
- Contains maleimide reactive group for thiol conjugation
- Disulfide-containing spacer enables cleavable release under reducing conditions
- Suitable for synthesis of antibody-drug conjugates and linker-payload constructs
- High purity for research applications
- Available in small package sizes for lab-scale synthesis