Methoxybenzoic acids and derivatives

Medchemexpress LLC Methoxy-x04 | 863918-78-9 | MFCD25563254 | 98.5% | 344.4 g/mol | C23H20O3 | 25 MG

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

Methoxy-X04 is a blood-brain barrier-permeant fluorescent probe that selectively binds beta-pleated sheets in dense core amyloid β (Aβ) plaques. It is used for in vivo imaging and for histological staining of Aβ plaques, tangles, and cerebrovascular amyloid, and exhibits high affinity for Aβ fibrils.

• Blood-brain barrier permeant fluorescent probe.
• Selectively binds beta-pleated sheets in amyloid β plaques.
• Suitable for in vivo imaging and histological staining.
• High binding affinity for Aβ fibrils (Ki = 26.8 nM).
• High purity supply (>98% by HPLC).

Medchemexpress LLC 4-[(E)-2-[4-[(E)-2-(4-hydroxyphenyl)ethenyl]-3-methoxyphenyl]ethenyl]phenol | 863918-78-9 | MFCD25563254 | 98.5% | 344.40 | C23H20O3 | 1 ML

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

Methoxy-X04 is a blood-brain barrier permeant fluorescent dye that selectively binds beta-pleated sheets in dense-core amyloid-β plaques for in vivo and ex vivo imaging and histological staining. It is supplied as a 10 mM solution in DMSO or as a solid for reconstitution.

• Blood-brain barrier permeant fluorescent probe.
• Selective binding to amyloid-β plaques, tangles, and cerebrovascular amyloid.
• Excitation 370 nm; emission 452 nm for blue fluorescence detection.
• Available as 10 mM solution in DMSO or as solids in multiple pack sizes.
• High purity (~98.5%) and molecular weight 344.40 Da.