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Reactive nonmetal salts are ionic compounds formed with elements classified as reactive nonmetals. These salts are available in a variety of chemical compositions and quantities, and most are formed from the five gaseous reactive nonmetals.
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IR415 is a small-molecule research inhibitor that blocks hepatitis B virus (HBV) replication by binding HBx and reversing HBx-mediated suppression of RNA interference. It is intended for in vitro studies of HBV replication and HBx biology.
Potent HBx binder with a reported Kd of about 2 nM.
Useful for in vitro HBV replication and mechanism-of-action studies.
High reported chemical purity (99.66%).
Molecular weight ≈ 296.34 and formula C13H14F2N4S.
Recommended powder storage: -20°C for long-term stability.
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IR415 is a research compound that inhibits hepatitis B virus (HBV) replication by blocking HBx activity. It selectively binds HBx (reported Kd = 2 nM) and reverses HBx-mediated suppression of RNA interference; characterized for dose-dependent inhibition of HBx in vitro.
Selective HBx inhibitor (Kd = 2 nM).
Demonstrated dose-dependent inhibition of HBx activity in cell assays.
Chemical formula C13H14F2N4S; molecular weight 296.34.
High purity (reported ≥98% by HPLC).
Available as a powdered research reagent; store powder at -20°C for long-term stability.
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Nicotredole (tryptamide) is an orally active small molecule with anti-inflammatory and analgesic activity. It shows anti-inflammatory potency comparable to phenylbutazone while exhibiting only weak ulcerogenic effects, making it useful for preclinical research into inflammation and pain pathways.
Orally active anti-inflammatory and analgesic agent.
Comparable anti-inflammatory potency to phenylbutazone.
Weak ulcerogenic activity relative to reference compounds.
High chemical purity (approximately 99.9%).
Available as solid and as 10 mM solution in DMSO for in vitro use.
Suitable for preclinical pharmacology and mechanism-of-action studies.
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Yangambin is a furofuran lignan supplied for laboratory research that functions as a calcium-channel inhibitor and platelet-activating factor (PAF) receptor antagonist. It reduces intracellular Ca2+ in vascular smooth muscle cells and has reported antiallergic and anti-inflammatory activity in vitro.
Acts as a calcium-channel inhibitor and PAF receptor antagonist.
Shows antiallergic and anti-inflammatory activity in vitro.
High purity (≈98.3%), suitable for biochemical and pharmacological assays.
Soluble in DMSO (50 mg/mL) and compatible with several in vivo formulations (≥1.25 mg/mL reported).
Furofuran lignan chemical class, C24H30O8, MW 446.49 Da.
Store at 4°C protected from light; in solution store at -80°C (6 months) or -20°C (1 month).
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FD-IN-1 is an orally bioavailable and selective factor D (FD) inhibitor with an IC50 of 12 nM. This compound targets the alternative complement pathway of the innate immune system, and also exhibits inhibitory activity against factor XIa (FXIa) and Tryptase β2.
Selective factor D inhibitor (IC50 of 12 nM)
Inhibits factor XIa (FXIa) and Tryptase β2
Exhibits high oral bioavailability (83% in mice, 70% in dogs)
Demonstrates systemic and local ocular suppression of AP activation
Terminal elimination half-lives of 1.6 hours in mice and 3.8 hours in dogs
Fully inhibits AP pathway for up to 10 hours at 10 mg/kg dose in human FD knock-in mice
Molecular weight of 377.43 and chemical formula C23H23NO4
Appears as a white to off-white solid
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