Macrolide lactams

Selleck Chemical LLC FK-3311 S2595-5mg

FK-3311 (COX-2 Inhibitor V) is a selective cell-permeable and orally available inhibitor of cyclooxygenase-2 (COX-2) with antiinflammatory FK-3311 has protective effects against hepatic warm ischemia-reperfusion injury by marked inhibition of TxA2

Selleck Chemical LLC Tacrolimus monohydrate

Tacrolimus monohydrate (Tacrolimus FK506) is a macrolide antibiotic that primarily acts as an inhibitor of calcineurin phosphatase by binding to FK506 binding protein (FKBP) This inhibition blocks calcium-dependent processes including interleukin-2 gene transcription nitric oxide synthase activation cell degranulation and apoptosis and also has immunosuppressive neuroregenerative and neuroprotective properties

Selleck Chemical LLC Tacrolimus monohydrate

Tacrolimus monohydrate (Tacrolimus FK506) is a macrolide antibiotic that primarily acts as an inhibitor of calcineurin phosphatase by binding to FK506 binding protein (FKBP) This inhibition blocks calcium-dependent processes including interleukin-2 gene transcription nitric oxide synthase activation cell degranulation and apoptosis and also has immunosuppressive neuroregenerative and neuroprotective properties

Selleck Chemical LLC Tacrolimus monohydrate

Tacrolimus monohydrate (Tacrolimus FK506) is a macrolide antibiotic that primarily acts as an inhibitor of calcineurin phosphatase by binding to FK506 binding protein (FKBP) This inhibition blocks calcium-dependent processes including interleukin-2 gene transcription nitric oxide synthase activation cell degranulation and apoptosis and also has immunosuppressive neuroregenerative and neuroprotective properties

Selleck Chemical LLC Tacrolimus monohydrate

Tacrolimus monohydrate (Tacrolimus FK506) is a macrolide antibiotic that primarily acts as an inhibitor of calcineurin phosphatase by binding to FK506 binding protein (FKBP) This inhibition blocks calcium-dependent processes including interleukin-2 gene transcription nitric oxide synthase activation cell degranulation and apoptosis and also has immunosuppressive neuroregenerative and neuroprotective properties

Selleck Chemical LLC Tacrolimus (FK506) S5003-1g

Tacrolimus (FK506) is a 23-membered macrolide lactone it reduces peptidyl-prolyl isomerase activity in T cells by binding to the immunophilin FKBP12 (FK506 binding protein) creating a new complex Tacrolimus also inhibits the phosphatase activity of calcineurin Tacrolimus induces vascular endothelial autophagy

Selleck Chemical LLC Ascomycin

Ascomycin (FK520 FR 900520 Immunomycin) an FK-506 analog is a neutral macrolide immunosuppressant which prevents rejection after an organ transplant Phase 3

Medchemexpress LLC (+)-(R)-[(E)-3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)acryloyl]-2-piperidineethanol | 121524-18-3 | 99.2% | 375.46 | C23H25N3O2 | 50 MG

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FK 453 is a non-xanthine adenosine A1 receptor antagonist (compound 1d) used in pharmacological research. It is reported as potent and selective, with an IC50 of 17.2 nM. The compound has chemical formula C23H25N3O2, molecular weight 375.46, and reported purity 99.20%.

• Potent and selective A1 receptor antagonist (IC50 17.2 nM).
• High reported purity suitable for research use (99.2%).
• Chemical formula C23H25N3O2 and molecular weight 375.46.
• Available in small research quantities, for example 50 mg.
• Supplied with supporting analytical data such as COA, HPLC, and LCMS.

Medchemexpress LLC Fk 453 (compound 1d) | 121524-18-3 | 99.2% | 375.46 g·mol⁻¹ | C23H25N3O2 | 5 MG

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FK 453 (compound 1d) is a potent and selective adenosine A1 receptor antagonist (IC50 17.2 nM) intended for research use. It is a non-xanthine small molecule used in pharmacological studies to probe A1 receptor function and ligand interactions.

• Potent adenosine A1 antagonist (IC50 17.2 nM).
• High purity 99.2%.
• Molecular weight 375.46 g·mol⁻¹.
• Chemical formula C23H25N3O2.
• Supplied as 5 mg solid for laboratory research.
• Suitable for in vitro pharmacology and receptor binding assays.

Medchemexpress LLC FK 453 | 121524-18-3 | 99.2% | 375.46 | C23H25N3O2 | 25 MG

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FK 453 is a research-use adenosine A1 receptor antagonist (compound 1d) characterized by potent activity and a defined chemical profile. It exhibits an IC50 of 17.2 nM and is supplied as a high-purity powder with recommended storage conditions for both powder and solution forms.

• Potent, selective adenosine A1 receptor antagonist (IC50 = 17.2 nM).
• High purity: 99.2%.
• Molecular formula C23H25N3O2 and molecular weight 375.46.
• Available in multiple small-scale package sizes, including 25 mg.
• Storage recommended as powder at -20°C (3 years) or 4°C (2 years).
• In solvent storage guidance: -80°C (6 months) or -20°C (1 month).
• For research use only; not for human or clinical use.