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Macrolide lactams

Compounds that are analog of macrolides that contain lactam rings in place of lactone rings; they are a class of antibiotics. Lactam rings are nitrogen analogs of lactone rings.

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Medchemexpress LLC FK 3311 | 116686-15-8 | MFCD00876455 | 98.7% | C15H13F2NO4S | 50 MG
SDP

FK 3311, also known as COX-2 Inhibitor V, is a selective inhibitor of COX-2 with anti-inflammatory properties. It is intended for research use only.

  • Targets COX-2
  • Exhibits anti-inflammatory activity by inhibiting adjuvant-induced arthritis
  • Demonstrates analgesic effects in the acetic acid-induced writhing assay
  • Improves L-PVR, CO, PaO(2), and WDR in a canine model of pulmonary ischemia-reperfusion injury
  • Reduces histological tissue edema and PMN infiltration
  • Lowers serum TxB(2) levels and improves survival rate in pulmonary ischemia-reperfusion injury
  • Improves survival rates and lowers serum GOT/GPT levels in liver transplantation with ischemia-reperfusion injury

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