Cinnamic acids and derivatives
Selleck Chemical LLC p-Coumaric Acid S4759-25mg
p-Coumaric acid (4-Hydroxycinnamic acid P-Hydroxycinnamic acid 4-Coumaric acid Trans-p-Coumaric acid para-Coumaric Acid) is a hydroxy derivative of cinnamic acid found in a variety of edible plants and is reported to have antioxidant anti-inflammatory and antimicrobial activity
Selleck Chemical LLC 2-Methoxycinnamic acid
2-Methoxycinnamic acid (AI3-11206) is a cinnamic acid with magnetic properties
Selleck Chemical LLC Trans-ferulic acid-E0653-100MG
Trans-ferulic acid is a potent activator of AMPKunder high glucose condition
Selleck Chemical LLC AMG-458 S2747-50mg
AMG 458 is a potent c-Met inhibitor with Ki of 1 2 nM 350-fold selectivity for c-Met than VEGFR2 in cells
Selleck Chemical LLC Tyrphostin AG 1296
Tyrphostin AG 1296 is an inhibitor of PDGFR with IC50 of 0 3-0 5 M no activity to EGFR Tyrphostin AG1296 inhibits FGFR and c-Kit with IC50 of 12 3 M and 1 8 M in Swiss 3T3 cells Tyrphostin AG1296 induces dramatic apoptosis in A375R cells
Selleck Chemical LLC Ferulic Acid S2300-10mM/1mL
Ferulic Acid (Fumalic) is a hydroxycinnamic acid and a type of organic compound found in the Ferula assafoetida L or Ligusticum chuanxiong Ferulic acid is a novel fibroblast growth factor receptor (FGFR) inhibitor with IC50s of 3 78 M and 12 5 M for FGFR1 and FGFR2 respectively
Selleck Chemical LLC BLU 451-E1877-100MG
BLU 451 is a central nervous system (CNS)-penetrant wild-type EGFR-sparing covalent inhibitor of epidermal growth factor receptor (EGFR) exon 20 insertion (Ex20ins) with an IC50 of 7-78 nM It also exhibits a potent anti-tumor efficacy
Selleck Chemical LLC BLU 451-E1877-25MG
BLU 451 is a central nervous system (CNS)-penetrant wild-type EGFR-sparing covalent inhibitor of epidermal growth factor receptor (EGFR) exon 20 insertion (Ex20ins) with an IC50 of 7-78 nM It also exhibits a potent anti-tumor efficacy
Selleck Chemical LLC Ferulic acid methyl ester S5451-25mg
Ferulic acid methyl ester (Methyl Ferulate Methyl 4 -hydroxy-3 -methoxycinnamate) is a lipophilic derivative of ferulic acid which is a hydroxycinnamic acid that is abundant in plants It shows the strongest antioxidant activity and can protect against inflammation and cancer
Selleck Chemical LLC -cyano-4-hydroxycinnamic acid(-CHCA) 200mg 28166-41-8
4-Chloro-?-cyanocinnamic acid (?-CHCA) is a classic monocarboxylate transporters (MCT) inhibitor. ?-cyano-4-hydroxycinnamate (CHC) has a 10-fold selectivity for MCT1 compared to other MCTs. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC BLU 451-E1877-1G
BLU 451 is a central nervous system (CNS)-penetrant wild-type EGFR-sparing covalent inhibitor of epidermal growth factor receptor (EGFR) exon 20 insertion (Ex20ins) with an IC50 of 7-78 nM It also exhibits a potent anti-tumor efficacy
Selleck Chemical LLC AG 494
AG-494 a member of the tyrphostin family of tyrosine kinase inhibitors is a potent inhibitor of EGF receptor autophosphorylation (IC50 1 2 M) and EGF-dependent cell growth (IC50 6 M)
Selleck Chemical LLC Curcumin S1848-1g
Curcumin (Diferuloylmethane Natural Yellow 3 Turmeric yellow) is the principal curcuminoid of the popular Indian spice turmeric which is a member of the ginger family (Zingiberaceae) It is an inhibitor of p300 histone acetylatransferase IC50 25 M and Histone deacetylase (HDAC) activates Nrf2 pathway and supresses the activation of NF- B Curcumin induces mitophagy autophagy apoptosis and cell cycle arrest with antitumor activity Curcumin reduces renal damage associated with rhabdomyolysis by decreasing ferroptosis-mediated cell death Curcumin exhibits anti-infective properties against various human pathogens like the influenza virus hepatitis C virus HIV and so on
Selleck Chemical LLC BLU 451-E1877-5MG
BLU 451 is a central nervous system (CNS)-penetrant wild-type EGFR-sparing covalent inhibitor of epidermal growth factor receptor (EGFR) exon 20 insertion (Ex20ins) with an IC50 of 7-78 nM It also exhibits a potent anti-tumor efficacy
Selleck Chemical LLC Tyrphostin AG-528
Tyrphostin AG-528 (Tyrphostin B66) is a potent inhibitor of epidermal growth factor receptors (EGFR) and ErbB2/HER2 with IC50 of 4 9 M and 2 1 M respectively Tyrphostin AG-528 exhibits anticancer activity