Guanidines
Selleck Chemical LLC Metformin
Metformin (1 1-Dimethylbiguanide) a widely used drug for treatment of type 2 diabetes activates AMP-activated protein kinase (AMPK) in hepatocytes Metformin promotes mitophagy in mononuclear cells Metformin induces apoptosis of lung cancer cells through activating JNK/p38 MAPK pathway and GADD153
Selleck Chemical LLC Metformin
Metformin (1 1-Dimethylbiguanide) a widely used drug for treatment of type 2 diabetes activates AMP-activated protein kinase (AMPK) in hepatocytes Metformin promotes mitophagy in mononuclear cells Metformin induces apoptosis of lung cancer cells through activating JNK/p38 MAPK pathway and GADD153
Selleck Chemical LLC Metformin HCl S1950-5g
Metformin HCl (1 1-Dimethylbiguanide HCl) decreases hyperglycemia in hepatocytes primarily by suppressing glucose production by the liver (hepatic gluconeogenesis) Metformin promotes mitophagy in mononuclear cells Metformin induces apoptosis of lung cancer cells through activating JNK/p38 MAPK pathway and GADD153
Selleck Chemical LLC 1-Phenylbiguanide S2578-25mg
1-Phenylbiguanide (Phenylbiguanide PBG N-Phenylbiguanide) is a 5-hydroxytryptamine3 (5-HT3) receptor agonist with EC50 of 3 0 M
Selleck Chemical LLC Metformin
Metformin (1 1-Dimethylbiguanide) a widely used drug for treatment of type 2 diabetes activates AMP-activated protein kinase (AMPK) in hepatocytes Metformin promotes mitophagy in mononuclear cells Metformin induces apoptosis of lung cancer cells through activating JNK/p38 MAPK pathway and GADD153
Selleck Chemical LLC Metformin HCl S1950-1g
Metformin HCl (1 1-Dimethylbiguanide HCl) decreases hyperglycemia in hepatocytes primarily by suppressing glucose production by the liver (hepatic gluconeogenesis) Metformin promotes mitophagy in mononuclear cells Metformin induces apoptosis of lung cancer cells through activating JNK/p38 MAPK pathway and GADD153
Medchemexpress LLC Phenylbiguanide hydrochloride | 55-57-2 | MFCD00035040 | 99.8% | 213.67 g/mol | C8H12ClN5 | 10 G
Phenylbiguanide hydrochloride is the hydrochloride salt of phenylbiguanide, a selective 5-HT3 receptor agonist supplied as a high-purity research chemical for in vitro pharmacology and neuroscience studies. The material is characterized with standard identifiers, purity specification, and storage guidance for laboratory use.
- Selective 5-HT3 receptor agonist with an EC50 of 3.0 ± 0.1 μM.
- Chemical identifiers: CAS 55-57-2; formula C8H12ClN5; molecular weight 213.67 g/mol.
- High purity solid (≈99.8%) suitable for analytical and pharmacological assays.
- Available in multiple lab-scale pack sizes (10 G-100 G) for research workflows.
- Storage: store at room temperature up to 3 years; in solvent, -80 °C (2 years) or -20 °C (1 year).
- For research use only; not for human or veterinary use.
Medchemexpress LLC 4-(2,6-dioxo-1-propyl-1,2,3,6-tetrahydropurin-8-yl)benzene-1-sulfonic acid | 152529-79-8 | 99.0% | 350.35 g/mol | C14H14N4O5S | 10 MG
PSB-1115 is a selective A2B adenosine receptor antagonist for pharmacological research. It inhibits TNBS-induced acetylcholine contraction in vitro and antagonizes NECA-induced inhibition of mucociliary clearance in vivo.
- Selective A2B adenosine receptor antagonist
- Purity 99.0%
- Molecular weight 350.35 g/mol
- Chemical formula C14H14N4O5S
- CAS number 152529-79-8
- Solubility: DMSO 100 mg/mL; H2O 10 mg/mL
- Storage: -20°C; in solvent -80°C (6 months)
- Intended for research use only
Medchemexpress LLC Phenylbiguanide | 55-57-2 | MFCD00035040 | 100.0% | 213.67 g/mol | C8H12ClN5 | 100 G
Phenylbiguanide hydrochloride is a research-grade small molecule used as a selective agonist of the 5-HT3 receptor in pharmacology and neuronal signaling studies. It exhibits an EC50 of approximately 3.0 μM and has documented solubility and stability data suitable for laboratory use.
- Selective 5-HT3 receptor agonist (EC50 ≈ 3.0 μM).
- Chemical identity: CAS 55-57-2; formula C8H12ClN5; molecular weight 213.67 g/mol.
- High purity for research applications (COA reports 99.96%).
- Soluble in DMSO (≈40 mg/mL); formulations reported for in vivo dosing.
- Stable as solid at room temperature; defined solvent storage conditions available.
- Suitable for GPCR and neuronal signaling assays and related pharmacology studies.
Medchemexpress LLC Imidodicarbonimidic diamide, N-methyl-, hydrochloride (1:1) | 1674-62-0 | ≥97.0% | 151.60 | 100 MG
Metformin impurity 1 is a chemical product from MedChemExpress, identified by CAS number 1674-62-0 and molecular weight 151.60. It is intended for research use in laboratory settings.
- White to off-white solid appearance.
- Purity of at least 97.0%.
- Stable under recommended storage conditions.
- Melting point range of 148-151 °C.
- Recommended storage at 4°C, sealed, away from moisture and light.
- Harmful if swallowed.
- For research use only.
Medchemexpress LLC PSB-1115 | 152529-79-8 | 99.0% | 350.35 g·mol⁻¹ | C14H14N4O5S | 100 MG
PSB-1115 is a selective A2B adenosine receptor antagonist used as a research tool to block A2B-mediated signaling in vitro and in vivo. It is reported to antagonize adenosine-mediated effects in animal models and to inhibit TNBS-induced responses.
- Selective A2B adenosine receptor antagonist for research use.
- High purity (99.0%) solid suitable for biological assays.
- Chemical formula C14H14N4O5S; molecular weight 350.35 g·mol⁻¹.
- Soluble in DMSO (100 mg/mL) and water (10 mg/mL) with sonication or warming.
- Recommended storage at -20°C; in solution, store at -80°C for long-term stability.
- Reported in vivo activity at 0.5 mg/kg (i.p.) in mouse mucociliary clearance studies.