Thiophenes
Selleck Chemical LLC GSK-LSD1 2HCl
GSK-LSD1 2HCl is an irreversible and selective LSD1 inhibitor with IC50 of 16 nM 1000 fold selective over other closely related FAD utilizing enzymes (i e LSD2 MAO-A MAO-B)
Selleck Chemical LLC TLR7/8 agonist 1 2HCl
TLR7/8 agonist 1 dihydrochloride is a toll-like receptor TLR7/TLR8 dual-agonistic imidazoquinoline TLR7/8 agonist 1 retains TLR7-agonistic activity with an EC50 of 20 nM
Selleck Chemical LLC BGP-15 2HCl
BGP-15 is a nicotinic amidoxime derivative with PARP inhibitory activity It has been demonstrated that BGP-15 protects against ischemia-reperfusion injury
Selleck Chemical LLC H 89 2HCl S1582-50mg
H 89 2HCl is a potent PKA inhibitor with Ki of 48 nM in a cell-free assay 10-fold selective for PKA than PKG 500-fold greater selectivity than PKC MLCK calmodulin kinase II and casein kinase I/II H 89 2HCl induces autophagy
Selleck Chemical LLC TLR7/8 agonist 1 2HCl
TLR7/8 agonist 1 dihydrochloride is a toll-like receptor TLR7/TLR8 dual-agonistic imidazoquinoline TLR7/8 agonist 1 retains TLR7-agonistic activity with an EC50 of 20 nM
Selleck Chemical LLC PRT-060318 2HCl
PRT-060318 (PRT318) is a novel selective inhibitor of the Syk tyrosine kinase with an IC50 of 4 nM as an approach to HIT treatment
Selleck Chemical LLC Lomerizine 2HCl S4084-50mg
Lomerizine dihydrochloride (KB-2796) is a relatively new L- and T-type calcium channel blocker used in the treatment of migraine
Selleck Chemical LLC Trifluoperazine 2HCl S3201-1g
Trifluoperazine (NSC-17474 RP-7623 SKF-5019) 2HCl is a dopamine D2 receptor inhibitor with IC50 of 1 1 nM Trifluoperazine also inhibits calmodulin (CaM)
Selleck Chemical LLC Cyclizine 2HCl S4139-50mg
Cyclizine 2HCl is a piperazine derivative with Histamine H1 receptor antagonist activity
Selleck Chemical LLC EPZ020411 2HCl
EPZ020411 is a potent and selective small molecule PRMT6 inhibitor with an IC50 of 10 nM
Selleck Chemical LLC THZ1 2HCl
THZ1 is a covalent CDK7 inhibitor which has the unprecedented ability to target a remote cysteine residue located outside of the canonical kinase domain providing an unanticipated means of achieving selectivity for CDK7
Selleck Chemical LLC 1400W 2HCl
1400W (N-(3-(Aminomethyl)benzyl)acetamidine) is a slow tight binding and highly selective inhibitor of inducible nitric-oxide synthase(iNOS)
Selleck Chemical LLC 1400W 2HCl
1400W (N-(3-(Aminomethyl)benzyl)acetamidine) is a slow tight binding and highly selective inhibitor of inducible nitric-oxide synthase(iNOS)
Selleck Chemical LLC BGP-15 2HCl
BGP-15 is a nicotinic amidoxime derivative with PARP inhibitory activity It has been demonstrated that BGP-15 protects against ischemia-reperfusion injury