Pyrrolidines
Enzo Life Sciences Bisindolylmaleimide X. hydrochloride (1mg). CAS: 145317-11-9
PKC inhibitor. Selective inhibitor of protein kinase C (PKC). Alternative name: Ro 31-8425. Formula: C26H24N4O2 . HCl. MW: 424.5 . 36.5. Purity: ≥95% (HPLC). Solubility: Soluble in DMSO or 100% ethanol. Long Term Storage: -20°C. Handling: Protect from light.
Enzo Life Sciences SB-415286 (5mg). CAS: 264218-23-7
Potent and selective inhibitor of GSK-3β (IC50=78nM). Stimulates glycogen synthesis in human liver cells and mimics other actions of insulin. Protects primary neurons from death induced by PI-3 kinase pathway inhibition suggesting therapeutic potential in neurodegenerative diseases and stroke. Purity: ≥98% (HPLC). Solubility: Soluble in DMSO, ethanol or methanol. Long Term Storage: -20°C.
Enzo Life Sciences Bisindolylmaleimide II (1mg). CAS: 137592-45-1
PKC inhibitor. Formula: C27H26N4O2. MW: 438.5. Purity: ≥97% (HPLC). Appearance: Orange solid. Solubility: Soluble in DMSO or 100% ethanol. Long Term Storage: -20°C. Handling: Protect from light.
Enzo Life Sciences Bisindolylmaleimide IV (1mg). CAS: 119139-23-0
PKC inhibitor. Alternative name: Ro 31-6233, Arcyriarubin A. Formula: C20H13N3O2. MW: 327.3. Purity: ≥95% (HPLC), single spot (TLC). Appearance: Red solid. Solubility: Soluble in DMSO or methanol. Long Term Storage: -20°C. Handling: Protect from light.
Enzo Life Sciences Bisindolylmaleimide V (5mg). CAS: 113963-68-1
Negative control for the protein kinase C (PKC)-inhibitory activity. Formula: C21H15N3O2. MW: 341.4. Purity: ≥98%. Solubility: Soluble in DMSO or methanol; very slightly soluble in 100% ethanol. Long Term Storage: -20°C.
Enzo Life Sciences Bisindolylmaleimide IV (5mg). CAS: 119139-23-0
Alternative name: Ro 31-6233, Arcyriarubin A. Formula: C20H13N3O2. MW: 327.3. Purity: ≥95% (HPLC), single spot (TLC). Appearance: Red solid. Solubility: Soluble in DMSO or methanol. Long Term Storage: -20°C. Handling: Protect from light.
Enzo Life Sciences Go-6983 (0.5mg). CAS: 133053-19-7
PKC inhibitor. Has been shown to selectively inhibit several PKC isoenzymes (IC50 = 7nM for PKCα and PKCβ; 6nM for PKCγ; 10nM for PKCδ; 60nM for PKCζ). The compound does not effectively inhibit PKCµ (IC50=20 µM) and therefore can be used to differentiate PKCµ from other isoforms. Purity: ≥95% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -20°C.
Enzo Life Sciences L-161-982 (5 mg). CAS: 147776-06-5
A potent and selective prostaglandin EP4 receptor antagonist. Purity: ≥98% (HPLC). Solubility: Soluble in DMSO (25 mg/ml). Long Term Storage: -20°C.
Enzo Life Sciences ET A receptor antagonist [BQ-123]. sodium salt (5mg). CAS: 136553-81-6
Highly potent and selective ETA antagonist. Formula: C31H42N6O7 . Na. MW: 633.7. Purity: ≥96%. Solubility: Soluble in water. Long Term Storage: -20°C. Use/Stability: Stable for at least 3 years after receipt when stored at -20°C. Stock solutions are stable for up to 3 months when stored at -20°C.
Enzo Life Sciences ET A receptor antagonist [BQ-123]. sodium salt (1mg). CAS: 136553-81-6
Highly potent and selective ETA antagonist. Formula: C31H42N6O7 . Na. MW: 633.7. Purity: ≥96%. Solubility: Soluble in water. Long Term Storage: -20°C. Use/Stability: Stable for at least 3 years after receipt when stored at -20°C. Stock solutions are stable for up to 3 months when stored at -20°C.
Enzo Life Sciences R-(-)-Rolipram (5mg). CAS: 85416-75-7
R-enantiomer of rolipram which is more active at inhibition of PDE IV, Ki=06 µM. 10-fold more active than S-rolipram at inhibition of PDE IV. Inhibits antigen-induced contraction of guinea-pig colonic smooth muscle, EC50=0.1 µM. Alternative name: R-(-)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone. Purity: ≥98% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: Ambient.
Enzo Life Sciences Bisindolylmaleimide III (1mg)
PKC inhibitor. Potent and selective inhibitor of protein kinase C (PKC). Formula: C23H20N4O2. MW: 384.4. Purity: ≥98%. Solubility: Soluble in methanol or DMSO. Long Term Storage: -20°C. Handling: Protect from light.
Enzo Life Sciences Bisindolylmaleimide III (5mg)
Potent and selective inhibitor of protein kinase C (PKC). Formula: C23H20N4O2. MW: 384.4. Purity: ≥98%. Solubility: Soluble in methanol or DMSO. Long Term Storage: -20°C.
Enzo Life Sciences ET A receptor antagonist [BQ-610] (1mg). CAS: 141595-53-1
30-fold more potent ETA antagonist than BQ-123 in pig aortic smooth muscle membrane assay, same activity as BQ-123 when tested on pig cerebellum membrane. Formula: C36H44N6O6. MW: 656.8. Long Term Storage: -20°C.
Enzo Life Sciences Bisindolylmaleimide X. hydrochloride (5mg). CAS: 145317-11-9
Selective inhibitor of protein kinase C (PKC). Alternative name: Ro 31-8425. Formula: C26H24N4O2 . HCl. MW: 424.5 . 36.5. Purity: ≥95% (HPLC). Solubility: Soluble in DMSO or 100% ethanol. Long Term Storage: -20°C.