Pyrroles
Selleck Chemical LLC Elbasvir
Elbasvir (MK8742) is an NS5A inhibitor preventing hepatitis C viral RNA replication and virion assembly Median EC50 values range from 0 2 to 3600 pmol/L based on genotype
Selleck Chemical LLC Quisinostat (JNJ-26481585) 2HCl S1096-5mg
Quisinostat (JNJ-26481585) 2HCl is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0 11 nM in a cell-free assay modest potent to HDACs 2 4 10 and 11 greater than 30-fold selectivity against HDACs 3 5 8 and 9 and lowest potency to HDACs 6 and 7 Phase 2
Selleck Chemical LLC Ac-YVAD-cmk-5mg
Ac-YVAD-cmk (Caspase-1 Inhibitor II) is a selective IL-1β converting enzyme (ICE) inhibitor with neuroprotective and anti-inflammatory effects, effectively suppresses the expression of IL-1β and IL-18.
Selleck Chemical LLC 1-Furfurylpyrrole
1-Furfurylpyrrole (N-Furfurylpyrrole) is a potential contributor of flavor and aroma to popcorn
Selleck Chemical LLC Ondansetron Hydrochloride Dihydrate S4748-50mg
Ondansetron is a highly specific and selective serotonin 5-HT3 receptor antagonist (Ki 6 16 nM) with low affinity for dopamine receptors
Selleck Chemical LLC Alosetron Hydrochloride S4694-20mg
Alosetron Hydrochloride (GR 68755C GR 68755X Lotronex) is the hydrochloride salt form of alosetron a potent and selective 5-HT3 receptor antagonist
Selleck Chemical LLC Mebhydrolin napadisylate S5018-25mg
Mebhydrolin Napadisylate (Diazoline Diazolin Incidal Omeril) is classified as an antihistamine drug classes used to treat allergies
Selleck Chemical LLC Indoximod
Indoximod a methylated tryptophan acts as an IDO (indoleamine-(2 3)-dioxygenase) pathway inhibitor and reverses IDO-mediated immune suppression Phase 2 This product has poor solubility animal experiments are available cell experiments please choose carefully
Selleck Chemical LLC Atorvastatin Calcium S2077-10mM/1mL
Atorvastatin Calcium is an inhibitor of HMG-CoA reductase used as a cholesterol-lowering medication that blocks the production of cholesterol Atorvastatin Calcium induces apoptosis and autophagy
Selleck Chemical LLC Bromoenol lactone-E1878-100MG
Bromoenol lactone((6E)-Bromoenol lactone) is a selective irreversible potent inhibitor of calcium-independent phospholipase A2 (iPLA2 ) with an IC50 value of 7 M It prevents antigen-stimulated exocytosis in mast cells without hindering Ca2 influx
Selleck Chemical LLC Atorvastatin Calcium S2077-1g
Atorvastatin Calcium is an inhibitor of HMG-CoA reductase used as a cholesterol-lowering medication that blocks the production of cholesterol Atorvastatin Calcium induces apoptosis and autophagy
Selleck Chemical LLC Sunitinib malate S1042-500mg
Sunitinib malate is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFR with IC50 of 80 nM and 2 nM in cell-free assays and also inhibits c-Kit Sunitinib Malate effectively inhibits autophosphorylation of Ire1 Sunitinib Malate increases both death receptor and mitochondrial-dependent apoptosis
Selleck Chemical LLC Corey Lactone Diol S5335-25mg
Corey Lactone Diol is a pharmaceutical intermediate
Selleck Chemical LLC Sacubitril hemicalcium salt S4426-1g
Sacubitril (AHU-377) hemicalcium salt a component of the heart failure medicine LCZ696 is a potent inhibitor of neprilysin (neutral endopeptidase NEP)
Selleck Chemical LLC Sacubitril hemicalcium salt S4426-100mg
Sacubitril (AHU-377) hemicalcium salt a component of the heart failure medicine LCZ696 is a potent inhibitor of neprilysin (neutral endopeptidase NEP)