Pyridines and derivatives
Medchemexpress LLC CellTracker CM-DiI (CM-DiI) | 180854-97-1 | 95% | 1051.49 | 50 UG
CellTracker CM-DiI (CM-DiI) is a lipophilic fluorochrome utilized for tracking the migration of lymphocytes. This compound is effective for detecting labeled cells within histological sections, with an excitation wavelength of 553 nm and an emission wavelength of 570 nm.
- Lipophilic fluorochrome.
- Feasible to detect labeled cells in histological sections.
- Excitation at 553 nm.
- Emission at 570 nm.
Medchemexpress LLC Phloxine B 100g | 18472-87-2 | 829.63 | C20H2Br4Cl4Na2O5 | 100 G
Phloxine B is a xanthene-based fluorescent dye supplied as a red, water-soluble powder for laboratory use. It is commonly used as a biochemical reagent and cytoplasmic counterstain in histology and microscopy, and is provided with supporting documentation for quality control.
- Fluorescent dye for staining and assay applications
- Water-soluble red powder suitable for laboratory preparations
- Used as a cytoplasmic counterstain in histology and microscopy
- Supplied with SDS, certificate of analysis, and spectral data
- Available in a 100 g laboratory pack
Medchemexpress LLC Delgocitinib | 1263774-59-9 | 99.6% | 310.35 | 50 MG
Delgocitinib is a specific Janus kinase (JAK) inhibitor. It demonstrates potent inhibitory activity against JAK1, JAK2, JAK3, and Tyk2 with IC50 values of 2.8, 2.6, 13, and 58 nM, respectively. It functions competitively with ATP and has shown effectiveness in suppressing various inflammatory responses both in vitro and in vivo.
- Inhibits all JAK subtypes.
- Competitively inhibits ATP binding to JAKs.
- Suppresses inflammatory responses.
- Reduces IFN-γ production.
- Prevents development of hind paw swelling and histological changes of inflammatory cell infiltration and synovial cell hyperplasia in relevant models.
- Inhibits radiographic and histological changes of bone and cartilage destruction in relevant models.
- Ameliorates inflammatory cell infiltration, synovial cell hyperplasia, and cartilage/bone destructions in histological and radiographic examinations.
Apexbio Technology LLC Alcian Blue & Nuclear Fast Red Staining Kit, pH2.5 500T
Alcian Blue Nuclear Fast Red Staining Kit (pH 2 5) is employed in histological staining to visualize acidic polysaccharides and related substances within biological specimens Alcian Blue a water-soluble cationic dye binds electively to negatively charged molecules containing carboxyl groups and sulfate groups rendering glycosaminoglycans hyaluronic acid glycoproteins and acidic mucins identifiable by a blue color At pH 2 5 carboxylated mucopolysaccharides and epithelial acidic mucins are preferentially stained whereas sulfated mucins are less intensely colored compared to staining at lower pH conditions (such as pH 1 0) Nuclear Fast Red serves as a counterstain staining nuclei red to offer clear histological contrast This staining procedure is typically utilized for assessing chondrogenic differentiation in mesenchymal stem cells cartilage-related histology and mucin-producing tissues The kit is provided ready-to-use without additional acidification procedures
Medchemexpress LLC Light green SF yellowish (Acid Green 5) | 5141-20-8 | 75.0% | 792.85 | 5 G
Light green SF yellowish (Acid Green 5) is a triarylmethane dye, a highly selective mitochondrial stain, usually available as a disodium salt with a maximum absorption value of 629 nm. It can be used as a histological stain for collagen and is a critical component of Papanicolaou stains.
- Triarylmethane dye
- Highly selective mitochondrial stain
- Usually available as a disodium salt
- Maximum absorption value of 629 nm
- Can be used as a histological stain for collagen
- Critical component of Papanicolaou stains
Medchemexpress LLC Basic blue 26 (Victoria blue B) | 2580-56-5 | MFCD00011878 | 92.3% | 506.08 g/mol | C33H32ClN3 | 500 MG
Basic blue 26 (Victoria blue B) is a synthetic cationic triarylmethane dye used in laboratory staining and biochemical assays, and as a colorant in textiles, paper, and leather. It delivers a bright blue color with reliable performance in histological and analytical applications.
- Synthetic cationic triarylmethane dye suitable for staining and assays.
- Bright blue color with strong chromatic properties.
- Purity typically around 92.3% as supplied.
- Available in small laboratory pack sizes for research use.
- Suitable for histology, microbiology, and colorant applications.
Medchemexpress LLC Bouin's solution | 1 L
Bouin's solution is a compound fixative utilized in histology, composed of saturated picric acid, formaldehyde, and acetic acid.
- Compound fixative used in histology
- Composed of saturated picric acid, formaldehyde, and acetic acid
- Liquid appearance
- Light yellow to yellow color
- Store at room temperature, protected from light
- In solvent, store at -80°C for 1 year or -20°C for 6 months
- Solubility in DMSO: 200 mg/mL (in vitro, requires ultrasonication)
Medchemexpress LLC KAG-308 | 1215192-68-9 | 98.6% | 25 MG
KAG-308 is a potent, selective, and orally active agonist of the EP4 receptor (a prostaglandin E2 receptor subtype). It suppresses colitis and promotes histological mucosal healing, and potently inhibits TNF-α production.
- Potent, selective, and orally active EP4 receptor agonist
- Suppresses colitis and promotes histological mucosal healing
- Potently inhibits TNF-α production
- Ki and EC50 for human EP4 receptor: 2.57 nM and 17 nM, respectively
- More selective over EP1, EP2, EP3, and IP receptor
Medchemexpress LLC Erythrosin B sodium salt | 568-63-8 | MFCD00144257 | 85.0% | 879.86 | C20H6I4Na2O5 | 10 MG
Erythrosin B sodium salt is a water-soluble, tetraiodinated xanthene dye supplied for research and biochemical assays. It is used as a colorant, stain, and indicator in analytical and histological applications, and is provided in small, laboratory-scale quantities with documented composition and purity for identification and handling.
Medchemexpress LLC Azophloxine | 3734-67-6 | 99.7% | 509.42 | 5 G
Azophloxine, also known as acid red 1 (AR1), is a member of the synthetic red azo dye family.
- Functions as a fluorescent dye.
- Suitable for histological analysis.
- Intended for research use only.
Medchemexpress LLC Acriflavine | 8048-52-0 | MFCD00064307 | 98.0% | 259.73 g/mol | C14H14ClN3 | 25 MG
Acriflavine is an acridine-based fluorescent dye and antiseptic reagent used in biological research for nucleic acid labeling, histological staining, and studies of protease activity and viral replication. It is supplied as a solid or as a prepared aqueous solution and is accompanied by product documentation for proper handling and storage.
- Fluorescent acridine dye for nucleic acid labeling.
- Used in histological staining and fluorescence assays.
- Reported inhibitory activity against papain-like proteases.
- Available as solid powder and as an aqueous solution format.
- Includes product data sheet and safety data sheet for handling guidance.
Medchemexpress LLC Hematein | 475-25-2 | 65.3% | 1 G
Hematein is the oxidized derivative of hematoxylin used as a histological dye and research reagent. It stains cell nuclei and has been reported to act as an allosteric casein kinase II inhibitor (IC50 ≈ 0.74 μM). The compound has formula C16H12O6 and molecular weight 300.26.
- Used as a nuclear stain in histology and microscopy.
- Acts as an allosteric casein kinase II inhibitor (IC50 ≈ 0.74 μM).
- Available in multiple pack sizes for flexible research use.
- Chemical formula C16H12O6; molecular weight 300.26.
- Typical purity reported at 65.25% (lot-dependent).
Medchemexpress LLC KAG-308 | 1215192-68-9 | 99.6% | 460.52 | 5 MG
KAG-308 is a potent, selective, and orally active agonist of the EP4 receptor (a prostaglandin E2 receptor subtype). It effectively suppresses colitis, promotes histological mucosal healing, and potently inhibits TNF-α production. KAG-308 demonstrates high selectivity for the human EP4 receptor over other prostaglandin receptors like EP1, EP2, EP3, and IP receptors.
- Potent, selective, and orally active EP4 receptor agonist
- Suppresses colitis and promotes histological mucosal healing
- Potently inhibits TNF-α production
- Exhibits high selectivity for human EP4 receptor
Medchemexpress LLC Azd2389 | 2791472-12-1 | 99.7% | 411.48 | 1 ML
AZD2389 is a potent and orally active FAP inhibitor, designed for the study of metabolic dysfunction-associated steatohepatitis. This compound has shown to increase intact α2-antiplasmin and improve non-alcoholic fatty liver disease (NAFLD) activity scores and histological fibrosis in cynomolgus monkeys with diet-induced, biopsy-confirmed metabolic dysfunction-associated steatohepatitis (MASH) (F1/2 fibrosis).
- Potent and orally active FAP inhibitor
- Can be used for the study of metabolic dysfunction-associated steatohepatitis
- Increases intact α2-antiplasmin in vivo
- Improves non-alcoholic fatty liver disease (NAFLD) activity score and histological fibrosis in relevant animal models
Medchemexpress LLC Hematein | 475-25-2 | 1 ML
Hematein is the oxidized derivative of hematoxylin used as a histological stain and as a biochemical probe. It acts as an allosteric inhibitor of casein kinase II and has reported activity against Akt phosphorylation and the Wnt/TCF pathway. Supplied as milligram-scale powder or as a ready-to-use 10 mM solution in DMSO, it is intended for in vitro research use.
- Used for histological staining and nuclear visualization.
- Allosteric casein kinase II inhibitor in biochemical assays.
- Available as 10 mM solution in DMSO (1 ML) or as solid powder.
- Molecular formula C16H12O6; molecular weight 300.26 g/mol.
- Solubility and storage guidance provided for research applications.