Pyridazines and derivatives
Medchemexpress LLC 3-pyridin-3-ylpropyl (2S)-1-(3,3-dimethyl-2-oxopentanoyl)pyrrolidine-2-carboxylate | 186452-09-5 | MFCD00953146 | 99.8% | 360.45 g/mol | C20H28N2O4 | 25MG
GPI-1046 is an orally active, non-immunosuppressive immunophilin ligand with reported neuroprotective properties. It has been shown to reduce ethanol intake by upregulating the glutamate transporter GLT1 and to improve HIV-associated sensory neuropathy by attenuating store-operated calcium (SOC) entry. The compound is provided as a high-purity research chemical in solid and ready-to-use DMSO formulations for preclinical pharmacology studies.
- Has neuroprotective activity demonstrated in preclinical studies.
- Upregulates the glutamate transporter GLT1 in relevant brain regions.
- Attenuates store-operated calcium entry implicated in neuropathy.
- Provided at high reported purity for research applications.
- Available as solid packs and DMSO solutions for dosing flexibility.
Medchemexpress LLC 3-pyridin-3-ylpropyl (2S)-1-(3,3-dimethyl-2-oxopentanoyl)pyrrolidine-2-carboxylate | 186452-09-5 | MFCD00953146 | 99.8% | 360.4 g/mol | C20H28N2O4 | 50MG
GPI-1046 is a small-molecule immunophilin ligand reported to have neuroprotective effects and to modulate glutamate transporter activity. It is supplied in small laboratory pack sizes, typically as a DMSO solution, for preclinical research use only.
- Chemical formula C20H28N2O4.
- Molecular weight 360.4 g/mol.
- CAS number 186452-09-5.
- Purity 99.8%.
- Available as solution in DMSO and multiple small pack sizes.
- Intended for preclinical research use only.
eMolecules 7-Bromo-phthalazin-1-ol | 152265-57-1 | MFCD20278341 | 5g
J & W PharmLab LLC | 7-Bromo-phthalazin-1-ol | 5g | 289355836 | 70R0278 | 96.000 | 152265-57-1 | MFCD20278341 | 225.045 | C8H5BrN2O
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