Piperidines
Selleck Chemical LLC Naftopidil DiHCl S1387-25mg
Naftopidil DiHCl (Flivas KT-611 Avishot BM-15275) is a selective 5-HT1A and 1-adrenergic receptor antagonist with IC50 of 0 1 M and 0 2 M respectively
Selleck Chemical LLC Telacebec
Telacebec is a novel antituberculosis drug that targets Mycobacterium tuberculosis cellular energy production through inhibition of the mycobacterial cytochrome bc1 complex Telacebec (Q203 IAP6) is active against Mycobacterium tuberculosis H37Rv with MIC50 of 2 7 nM in culture broth medium
Selleck Chemical LLC Niraparib tosylate
Niraparib tosylate is a selective inhibitor of PARP1/PARP2 with IC50 of 3 8 nM/2 1 nM Niraparib increases formation of PARP-DNA complexes resulting in DNA damage apoptosis and cell death
Selleck Chemical LLC Ceritinib dihydrochloride-5mg
Ceritinib (Zykadia, LDK378) dihydrochloride is a selective, orally bioavailable and ATP-competitive inhibitor of ALK with IC50 of 0.2 nM. Ceritinib dihydrochloride also inhibits InsR, IGF-1R and STK22D with IC50 of 7 nM, 8 nM and 23 nM, respectively. Ceritinib exhibits antitomor activity.
Selleck Chemical LLC P110-5mg
P110 is a dynamin-related protein 1 (Drp1)-specific inhibitor that binds directly to Drp1.
Selleck Chemical LLC Alectinib S2762-50mg
Alectinib is a potent ALK inhibitor with IC50 of 1 9 nM in cell-free assays sensitive to L1196M mutation and higher selectivity for ALK than PF-02341066 NVP-TAE684 and PHA-E429
Selleck Chemical LLC GDC-0575
GDC-0575 is a potent and selective CHK1 inhibitor with an IC50 of 1 2 nM
Selleck Chemical LLC Tofacitinib Citrate | CAS No: 635702-64-7 | MDL No: MFCD01923393 | 1 g
Tofacitinib citrate | Purity: ≥98% | Mol Wt: 504.52 | CAS No: 635702-64-7 | MDL No: MFCD01923393 | 1g
Selleck Chemical LLC PNU 282987 HCl
PNU 282987 is a potent agonist of 7-containing neuronal nicotinic acetylcholine receptors with Ki value of 26 nM for the rat receptor
Selleck Chemical LLC Nelfinavir Mesylate S4282-10mM/1mL
Nelfinavir Mesylate is a potent HIV protease inhibitor with Ki of 2 nM
Selleck Chemical LLC BSJ-4-116-5mg
BSJ-4-116 is a specific degrader of cyclin-dependent kinase 12 (CDK12). BSJ-4-116 exhibits potent antiproliferative effects.
Selleck Chemical LLC Mepivacaine HCl S3155-1g
Mepivacaine is a tertiary amine used as a local anesthetic
Selleck Chemical LLC Mepivacaine S5392-25mg
Mepivacaine (Carbocaine) is a local anesthetic indicated for infiltration nerve block and epidural anesthesia
Selleck Chemical LLC Revefenacin S5258-2mg
Revefenacin (TD-4208 GSK-1160724) is a potent lung-selective long-acting muscarinic antagonist that may be for the treatment of respiratory disease