Piperazines
Carbosynth LLC. Biosynth Chemical Compound, 3-(2-Methoxyethyl)oxolan-3-amine hydrochloride
Biosynth Chemical Compound, 3-(2-Methoxyethyl)oxolan-3-amine hydrochloride
Selleck Chemical LLC PI-3065
PI-3065 is a selective p110 inhibitor with IC50 of 15 nM 70-fold selectivity over other PI3K family members
Selleck Chemical LLC PI-1840
PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor with IC50 of 27 nM with little effects on the other two major proteasome proteolytic activities trypsin-like (T-L) and postglutamyl-peptide-hydrolysis-like (PGPH-L)
Selleck Chemical LLC HA-100 dihydrochloride S2964-25mg
HA-100 dihydrochloride is an inhibitor of cGMP-dependent protein kinase (PKG) cAMP-dependent protein kinase (PKA) protein kinase C (PKC) and MLC-kinase with IC50 of 4 M 8 M 12 M and 240 M respectively
Selleck Chemical LLC Berbamine dihydrochloride S3609-25mg
Berbamine (BA BBM) dihydrochloride a traditional Chinese medicines extracted from Berberis amurensis (xiaoboan) is a novel inhibitor of bcr/abl fusion gene with potent anti-leukemia activity and also an inhibitor of NF- B Berbamine (BA BBM) dihydrochloride induces apoptosis in human myeloma cells and inhibits the growth of cancer cells by targeting Ca /calmodulin-dependent protein kinase II (CaMKII)
Selleck Chemical LLC CRT0066101 dihydrochloride
CRT0066101 dihydrochloride is a small molecule PKD family specific inhibitor which specifically blocks PKD1/2 activity and does not suppress PKC /PKC /PKC activity in multiple
Selleck Chemical LLC Berbamine dihydrochloride S3609-1g
Berbamine (BA BBM) dihydrochloride a traditional Chinese medicines extracted from Berberis amurensis (xiaoboan) is a novel inhibitor of bcr/abl fusion gene with potent anti-leukemia activity and also an inhibitor of NF- B Berbamine (BA BBM) dihydrochloride induces apoptosis in human myeloma cells and inhibits the growth of cancer cells by targeting Ca /calmodulin-dependent protein kinase II (CaMKII)
Selleck Chemical LLC Sardomozide dihydrochloride
Sardomozide dihydrochloride (CGP 48664A) is a potent inhibitor of S-adenosylmethionine decarboxylase (SAMDC) with an IC50 of 5 nM It is also a potent inhibitor of polyamine oxidase and exhibits with broad spectrum antiproliferative and antitumor activity
Selleck Chemical LLC Tilorone dihydrochloride S5020-1g
Tilorone dihydrochloride is a broad-spectrum orally active antiviral agent that activates interferon production It has antitumor anti-inflammatory properties
Selleck Chemical LLC LOX-IN-3 Dihydrochloride
LOX-IN-3 Dihydrochloride is an orally active and selective lysyl oxidase (LOX) inhibitor
Selleck Chemical LLC JTE-607 Dihydrochloride
JTE-607 Dihydrochloride is a prodrug compound that is converted to an active form by ester hydrolysis JTE-607 is a multiple cytokine production inhibitor that targets CPSF3 and inhibits pre-mRNA processing JTE-607 inhibits tumor necrosis factor (TNF)-alpha interleukin (IL)-1beta IL-6 IL-8 and IL-10 from LPS-stimulated human PBMCs with IC50 values of 11 nM 5 9 nM 8 8 nM 7 3 nM and 9 1 nM respectively
Selleck Chemical LLC Y-39983 Dihydrochloride
Y-39983 (Y-33075)Dihydrochloride is a selective rho-associated protein kinase(ROCK) inhibitor with an IC50 of 3 6 nM
Selleck Chemical LLC Simufilam dihydrochloride
Simufilam (PTI-125) Dihydrochloride is a small molecule modulator that preferentially binds altered FLNA and restores its native conformation restoring receptor and synaptic activities and reducing its 7 nAChR/TLR4 associations and downstream pathologies
Selleck Chemical LLC Sardomozide dihydrochloride
Sardomozide dihydrochloride (CGP 48664A) is a potent inhibitor of S-adenosylmethionine decarboxylase (SAMDC) with an IC50 of 5 nM It is also a potent inhibitor of polyamine oxidase and exhibits with broad spectrum antiproliferative and antitumor activity
Selleck Chemical LLC Fluphenazine dihydrochloride S4569-500mg
Fluphenazine dihydrochloride (Prolixin) is a phenothiazine-class D1DR and D2DR inhibitor It also inhibits Histamine H1 Receptor