Phenanthrolines
1, 10-Phenanthroline Monohydrate, ACS Reagent, Reagents
CAS: 5144-89-8 Molecular Formula: C12H10N2O Molecular Weight (g/mol): 198.23 InChI Key: PPQJCISYYXZCAE-UHFFFAOYSA-N Synonym: o-Phenanthroline Monohydrate IUPAC Name: 1,10-phenanthroline hydrate SMILES: O.C1=CN=C2C(C=CC3=CC=CN=C23)=C1
1,10-Phenanthroline, 0.3% w/v Acidified, Reagents
CAS: 7732-18-5 Molecular Formula: H2O Molecular Weight (g/mol): 18.02 InChI Key: XLYOFNOQVPJJNP-UHFFFAOYSA-N Synonym: o-Phenanthroline IUPAC Name: water SMILES: O
Selleck Chemical LLC Phenanthroline monohydrate
1 10-Phenanthroline is a classic chelating bidentate ligand for transition metal ions that has played an important role in the development of coordination chemistry It is an inhibitor of metallopeptidases
Selleck Chemical LLC o-Phenanthroline
o-Phenanthroline (1 10-Phenanthroline phen) a hypoxia-mimicking agent is a non-specific matrix metalloproteinase (MMP) inhibitor with IC50 of 110 5 M for Collagenase O-phenanthroline reduces the expression of MMP3 and MMP13 mRNA levels during chondrogenic differentiation of human chondrocytes (hChs) as well as after TNF /IL-1 exposure in an explant model o-Phenanthroline is also a metal chelator which prevents the induction of chromosomal aberrations in streptozotocin-treated cells and forms a red chelate with Fe2 that absorbs maximally at 510 nm
Medchemexpress LLC Nilotinib monohydrochloride monohydrate | 923288-90-8 | MFCD18251359 | 99.9% | 583.99 g·mol⁻¹ | C28H25ClF3N7O2 | 1 ML
Nilotinib monohydrochloride monohydrate is the hydrochloride monohydrate salt of nilotinib, a second-generation BCR-ABL tyrosine kinase inhibitor used in research to study BCR-ABL signaling, drug resistance, and mutant kinases. It is provided in concentrated stock-ready formats for biochemical, cell-based, and in vivo studies.
- Second-generation BCR-ABL tyrosine kinase inhibitor with activity against common resistant mutants.
- High chemical purity (~99.9% by LCMS) suitable for analytical and biological studies.
- Hydrochloride monohydrate salt form for improved solubility and handling.
- Molecular weight 583.99 g·mol⁻¹; formula C28H25ClF3N7O2.
- Soluble in DMSO (≈57 mM) and in acidified aqueous media; supplier provides stock preparation guidance.
- Intended for in vitro biochemical and cell-based assays and for in vivo formulation with appropriate vehicles.
Apexbio Technology LLC o-Phenanthroline monohydrate 5144-89-8 100mg
o-Phenanthroline monohydrate (CAS 5144-89-8) is a small-molecule inhibitor targeting matrix metalloproteinases (MMPs) It is designed to chelate metal ions thereby inhibiting the catalytic activity of MMPs and modulating related biological pathways o-Phenanthroline monohydrate exerts its biological activity primarily through metal ion chelation particularly by complexing with ferrous ions to form a chromophoric complex It demonstrates inhibitory activity in research involving MMPs and interference with chemically induced chromosomal aberrations Based on these pharmacological properties o-Phenanthroline monohydrate holds research potential in studies of cell migration tumor invasion signaling pathways and chromosome aberration modulation