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KTX-582 intermediate-2 is a synthetic chemical intermediate used in the preparation of KTX-582 and for antibody-drug conjugate (ADC) construction. It is used in medicinal chemistry applications related to IRAK4 degrader development.
Intermediate for synthesis and ADC preparation.
CAS number 2434850-07-2.
Molecular formula C21H27BrN4O5.
Molecular weight 495.37 g/mol.
Sold in small research quantities; supplier catalog indicates a 25 MG package.
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KTX-582 intermediate-2 is a synthetic intermediate used in the preparation of IRAK4 degrader molecules and for antibody-drug conjugate (ADC) synthesis. Supplied for research and synthetic applications.
Used as a synthetic intermediate for IRAK4 degrader development
Molecular weight 495.37
Chemical formula C21H27BrN4O5
CAS number 2434850-07-2
Storage: 4°C sealed, away from moisture; in solvent: -80°C for 6 months, -20°C for 1 month
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Sorbitan trioleate is an orally active nonionic surfactant with low toxicity (LD 200 mg/kg) Sorbitan trioleate can be used as an excipient such as surfactant emulsifier lubricant wetting agent dispersant thickener defoamer Pharmaceutical excipients or pharmaceutical auxiliaries refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations which can improve the stability solubility and processability of pharmaceutical preparations Pharmaceutical excipients also affect the absorption distribution metabolism and elimination (ADME) processes of co-administered drugs[1][2]
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Sorbitan trioleate is an orally active nonionic surfactant with low toxicity (LD 200 mg/kg) Sorbitan trioleate can be used as an excipient such as surfactant emulsifier lubricant wetting agent dispersant thickener defoamer Pharmaceutical excipients or pharmaceutical auxiliaries refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations which can improve the stability solubility and processability of pharmaceutical preparations Pharmaceutical excipients also affect the absorption distribution metabolism and elimination (ADME) processes of co-administered drugs[1][2]
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Sorbitan monododecanoate is a sorbitan ester nonionic surfactant and pharmaceutical excipient used as an emulsifier and stabilizer in formulations. It appears as a viscous, colorless to light yellow liquid and is used to improve solubility, stability, and processing in drug formulations and in industrial emulsification applications.
Nonionic surfactant and emulsifier.
Purity: 99.0%.
Viscous, colorless to light yellow liquid.
Solubility in DMSO: 100 mg/mL (requires ultrasonication).
Chemical formula C18H34O6; molar mass 346.5 g/mol.
Available in 2.5 kg package.
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KTX-582 intermediate-1 is a synthetic chemical intermediate supplied for research use and intended for use in the synthesis of IRAK4-degrading compounds and antibody-drug conjugate preparation. The material is provided as a powder and requires controlled storage conditions for stability.
used as a synthetic intermediate for research and development.
intended for laboratory research use only; not for human or clinical applications.
powder form with recommended storage conditions to preserve stability.
supports synthetic workflows including ADC preparation and targeted degradation studies.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Sorbitan trioleate is an orally active nonionic surfactant with low toxicity (LD 200 mg/kg) Sorbitan trioleate can be used as an excipient such as surfactant emulsifier lubricant wetting agent dispersant thickener defoamer Pharmaceutical excipients or pharmaceutical auxiliaries refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations which can improve the stability solubility and processability of pharmaceutical preparations Pharmaceutical excipients also affect the absorption distribution metabolism and elimination (ADME) processes of co-administered drugs[1][2]
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
KTX-582 intermediate-2 is a chemical intermediate used in the synthesis of IRAK4 degrader compounds and can be employed for antibody-drug conjugate (ADC) preparation. It is supplied as a solid with reported formula C21H27BrN4O5, molecular weight 495.37 g·mol⁻¹, and CAS number 2434850-07-2. Purity is batch-dependent and is provided on the supplier data sheet.
Used as an intermediate in the synthesis of IRAK4 degrader compounds.
Suitable for antibody-drug conjugate (ADC) preparation.
Supplied in small-scale quantities suitable for research use.
Reported molecular formula C21H27BrN4O5 and molecular weight 495.37 g·mol⁻¹.
CAS number 2434850-07-2 for unambiguous identification.
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