Oxetanes
Medchemexpress LLC Rbn-3143 | 2360853-16-1 | 99.3% | 449.54 g/mol | C22H28FN3O4S | 10 MG
RBN-3143 is a small-molecule, NAD+-competitive catalytic inhibitor of PARP14 with reported nanomolar potency (IC50 ≈ 4 nM). It inhibits PARP14-mediated ADP-ribosylation, stabilizes PARP14 in cell lines, and is provided for research use to support studies of PARP14 biology and inflammatory disease models.
- NAD+-competitive catalytic inhibitor of PARP14.
- Reported IC50 ≈ 4 nM against PARP14.
- Inhibits PARP14-mediated ADP-ribosylation in cell assays.
- Stabilizes PARP14 protein in cell lines.
- High reported chemical purity (~99.3%).
- Available in multiple research pack sizes for laboratory studies.
Medchemexpress LLC 3-Oxetanemethanol | 6246-06-6 | 88.11 | 100 MG
3-Oxetanemethanol is a biochemical reagent suitable for life science research. It can be used as a biological material or an organic compound. This product is for research use only.
- Biochemical reagent for life science research
- Suitable as a biological material or organic compound
- High purity of 99.7%
- Molecular weight: 88.11
- Chemical formula: C4H8O2
- Appears as a colorless to light yellow liquid
- Stable for 3 years at -20°C (pure form)
- Boiling point: 204.4°C (760 mmHg)
- Density: 1.093 g/cm3
Medchemexpress LLC Purfalcamine 10mg | 1038620-68-6 | 528.62 | C29H33FN8O | 10 MG
Purfalcamine is a selective Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1) inhibitor used for antimalarial research. It shows potent enzymatic inhibition (IC50 = 17 nM) and cellular activity (EC50 = 230 nM), causing parasite developmental arrest at the schizont stage. The compound is supplied for research use with characterized purity and composition.
- Selective PfCDPK1 inhibitor
- Potent enzymatic inhibition (IC50 17 nM)
- Demonstrates antimalarial cellular activity (EC50 230 nM)
- Causes parasite developmental arrest at the schizont stage
- High reported chemical purity (99.44%)
- Molecular formula C29H33FN8O and molecular weight 528.62
