Oxazinanes
Selleck Chemical LLC Higenamine hydrochloride S3960-5mg
Higenamine (Norcoclaurine ( -)-Demethylcoclaurine) also known as Norcoclaurine HCl is a non-selective 2 adrenoceptor agonist which is a chemical compound naturally occurring in a number of plants
Selleck Chemical LLC Formoterol Hemifumarate S2020-50mg
Formoterol Hemifumarate (Eformoterol CGP 25827A NSC 299587 YM 08316 Formoterol fumarate) is a potent selective and long-acting 2-adrenoceptor agonist used in the management of asthma and chronic obstructive pulmonary disease(COPD)
Selleck Chemical LLC Mebeverine Hydrochloride S5027-25mg
Mebeverine (Duspatalin Duspatal Colofac) a 3-phenylethylamine derivative of methoxybenzamine acts as a musculotropic antispasmodic agent
Selleck Chemical LLC Dasatinib hydrochloride S5254-10mM/1mL
Dasatinib hydrochloride (BMS-354825) is the hydrochloride salt form of dasatinib an inhibitor that targets Abl Src and c-Kit with IC50 of 1 nM 0 8 nM and 79 nM in cell-free assays respectively
Selleck Chemical LLC TAK-659 Hydrochloride
TAK-659 Hydrochloride is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3 2 nM It is selective against most other kinases but potent toward both SYK and FLT3
Selleck Chemical LLC TCEP Hydrochloride S4611-1g
TCEP (Tris(2-carboxyethyl)phosphine) hydrochloride a non-thiol reducing agent promotes NF- B-DNA binding in a dose-related manner Solutions are best fresh-prepared
Selleck Chemical LLC Dapiprazole Hydrochloride S5281-25mg
Dapiprazole Hydrochloride (Glamidolo Hydrochloride Reversil Hydrochloride) is the hydrochloride salt form of dapiprazole an alpha-adrenergic blocker used to reverse mydriasis after eye examination
Selleck Chemical LLC Oxybutynin hydrochloride S3117-5mg
Oxybutynin(MJ4309-1) is an anticholinergic medication used to relieve urinary and bladder difficulties
Selleck Chemical LLC Dasatinib hydrochloride S5254-1g
Dasatinib hydrochloride (BMS-354825) is the hydrochloride salt form of dasatinib an inhibitor that targets Abl Src and c-Kit with IC50 of 1 nM 0 8 nM and 79 nM in cell-free assays respectively
Selleck Chemical LLC OTS514 hydrochloride
OTS514 is a highly potent TOPK(T-LAK cell-originated protein kinase) inhibitor with an IC50 value of 2 6 nM OTS514 induces cell cycle arrest and apoptosis
Selleck Chemical LLC GPNA hydrochloride
GPNA hydrochloride (L- -glutamyl-p-nitroanilide hydrochloride) is a substrate of -glutamyltransferase (GGT) and an inhibitor of the glutamine transporter ASCT2 with an IC50 of 250 M in A549 cells It also inhibits Na -dependent carriers SNAT1 -2 -4 -5 and Na -independent leucine transporters LAT1/2 It can be widely used in research on pancreatic cancer breast cancer glioblastoma multiforme acute myelogenous leukemia and non-small-cell lung cancer
Selleck Chemical LLC Cytarabine hydrochloride
Cytarabine is a pyrimidine nucleoside analog that is used mainly in the treatment of leukemia It is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA
Selleck Chemical LLC ICCB-19 hydrochloride
ICCB-19 hydrochloride is an inhibitor of TNFRSF1A Associated Via Death Domain (TRADD) with IC50 of 1 12 M and 2 01 M for protecting Velcade-induced apoptosis in Jurkat cells and protecting RDA in MEFs respectively ICCB-19 indirectly inhibits Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) ICCB-19 effectively induces autophagy
Selleck Chemical LLC Crizotinib hydrochloride S5190-25mg
Crizotinib (PF-02341066) hydrochloride (Xalkori) inhibits tyrosine phosphorylation of c-Met and nucleophosmin (NPM)-anaplastic lymphoma kinase (ALK) with IC50 of of 11 nM and 24 nM in cell-based assays respectively Crizotinib hydrochloride is also a potent ROS1 inhibitor with Ki less than 0 025 nM Crizotinib induces autophagy through inhibition of the STAT3 pathway in multiple lung cancer cell lines