Lactones
Medchemexpress LLC Not listed on product page; chemical name not found in accessible SDS | 1206731-57-8 | 98.4% | 458.55 | C27H30N4O3 | 1 ML
This compound is a potent, selective histone deacetylase 6 (HDAC6) inhibitor used in biochemical and cellular research to probe HDAC6-related pathways. It also shows activity against metallo-β-lactamase domain-containing protein 2 (MBLAC2) and is supplied as a ready-to-use solution for in vitro studies.
- Potent HDAC6 inhibition (IC50 = 0.40 nM).
- Also inhibits MBLAC2, enabling dual-target studies.
- High purity (98.4%) suitable for biochemical assays.
- Molecular weight 458.55, formula C27H30N4O3.
- Supplied as 10 mM 1 mL solution in DMSO; solid formats available.
- Soluble ≥100 mg/mL in DMSO; store solutions at -80°C for long-term stability.
Selleck Chemical LLC GA-017-E1145-10MM/1ML
GA-017 inhibits the serine/threonine protein kinases large tumor suppressor kinase 1/2 (LATS1/2) which exerts inhibitory with IC50s against LATS1 and 2 of 4 10 0 79 and 3 92 0 42 nM respectively and competitively inhibits LATS1 and 2 against ATP with Ki (inhibition constant) values of 0 58 0 11 and 0 25 0 03 nM respectively
Selleck Chemical LLC Anti-mouse IFN-gamma-InVivo
The R4-6A2 monoclonal antibody reacts with mouse IFN (interferon gamma) which is a 20 kDa soluble pleiotropic cytokine and the sole member of the type II class of interferons The R4-6A2 antibody has been shown to neutralize both natural and recombinant IFN
Selleck Chemical LLC GA-017-E1145-25MG
GA-017 inhibits the serine/threonine protein kinases large tumor suppressor kinase 1/2 (LATS1/2) which exerts inhibitory with IC50s against LATS1 and 2 of 4 10 0 79 and 3 92 0 42 nM respectively and competitively inhibits LATS1 and 2 against ATP with Ki (inhibition constant) values of 0 58 0 11 and 0 25 0 03 nM respectively
Selleck Chemical LLC ATN-161
ATN-161 is a novel small peptide antagonist of integrin 5 1 It binds to several integrins including 5 1 and v 3 that play a role in angiogenesis and tumor progression
Selleck Chemical LLC δ-Valerolactone S3099-100mg
-Valerolactone (Tetrahydro-2H-pyran-2-one 5-Valerolactone oxan-2-one) is an endogenous metabolite
Selleck Chemical LLC GA-017-E1145-100MG
GA-017 inhibits the serine/threonine protein kinases large tumor suppressor kinase 1/2 (LATS1/2) which exerts inhibitory with IC50s against LATS1 and 2 of 4 10 0 79 and 3 92 0 42 nM respectively and competitively inhibits LATS1 and 2 against ATP with Ki (inhibition constant) values of 0 58 0 11 and 0 25 0 03 nM respectively
Selleck Chemical LLC Anti-mouse IFN-gamma-InVivo
The R4-6A2 monoclonal antibody reacts with mouse IFN (interferon gamma) which is a 20 kDa soluble pleiotropic cytokine and the sole member of the type II class of interferons The R4-6A2 antibody has been shown to neutralize both natural and recombinant IFN
Selleck Chemical LLC 3 3-Dimethylglutaric acid
3 3-Dimethylglutaric acid (3 3-Dimethylpentanedioate) is a compound that has occasionally found in human urine
Selleck Chemical LLC Butyrolactone 3-E1387-1MG
Butyrolactone 3 (MB-3) is a specifical small-molecule inhibitor of the histone acetyltransferase Gcn5 (IC50 100 M) which has a high affinity to the Gcn5 enzyme comparable to that of its natural substrate histone H3 Butyrolactone 3 shows weak inhibitory on CBP (IC50 0 5 mM) Butyrolactone 3 can be used in studies of cancer metabolic autoimmune and neurological diseases
Selleck Chemical LLC Anti-mouse IFN-gamma-InVivo
The R4-6A2 monoclonal antibody reacts with mouse IFN (interferon gamma) which is a 20 kDa soluble pleiotropic cytokine and the sole member of the type II class of interferons The R4-6A2 antibody has been shown to neutralize both natural and recombinant IFN
Selleck Chemical LLC ATN-161
ATN-161 is a novel small peptide antagonist of integrin 5 1 It binds to several integrins including 5 1 and v 3 that play a role in angiogenesis and tumor progression
Selleck Chemical LLC (3-Carboxypropyl)trimethylammonium chloride S3361-25mg
(3-Carboxypropyl)trimethylammonium chloride ( -Butyrobetaine BB hydrochloride) is an intermediary metabolite by gut microbes from dietary L-carnitine in mice
Selleck Chemical LLC ATN-161
ATN-161 is a novel small peptide antagonist of integrin 5 1 It binds to several integrins including 5 1 and v 3 that play a role in angiogenesis and tumor progression
Selleck Chemical LLC Gamma-Oryzanol S3957-25mg
Gamma-oryzanol (GO) a nutriactive phytochemical naturally occurring in crude rice bran oil is an antioxidant compound used to treat hyperlipidemia disorders of menopause and to increase the muscle mass -Oryzanol is a potent DNA methyltransferases (DNMTs) inhibitor in the striatum of mice -Oryzanol significantly inhibits the activities of DNMT1 (IC50 3 2 M) DNMT3a (IC50 22 3 M)