Imidolactams
Medchemexpress LLC (S,R,S)-AHPC-Me-PEG2-dabrafenib | 2769753-69-5 | 99.9% | C53H62F3N9O8S3 | 10MG
A selective small-molecule degrader that targets CDK17 and LIMK2, used as a chemical probe in preclinical research to study targeted protein degradation pathways.
- Selective degradation of CDK17 and LIMK2.
- High potency suitable for chemical biology studies.
- High purity: 99.9%.
- Available in multiple milligram-scale sizes for research use.
- Molecular weight 1106.31 g·mol⁻¹.
- Molecular formula C53H62F3N9O8S3.
- Intended for research use only.
Medchemexpress LLC DD-03-156 (S,R,S)-AHPC-Me-PEG2-dabrafenib | 2769753-69-5 | 99.9% | 1106.31 | 50 MG
DD-03-156 is a potent and selective degrader of CDK17 and LIMK2. Its selectivity and potency make it an advanced starting point for developing a chemical probe for the degradation of CDK17.
- Potent and selective degrader of CDK17 and LIMK2.
- Advanced starting point for developing a chemical probe for CDK17 degradation.
- Involves a VHL ligand, a linker, and a BRAF inhibitor.
- For research use only.
Medchemexpress LLC DD-03-156 | 2769753-69-5 | 99.9% | 1106.31 | 100 MG
DD-03-156 is a potent and selective degrader of CDK17 and LIMK2. Its exquisite selectivity and potency make it an advanced starting point for the development of a chemical probe for the degradation of CDK17. It includes a VHL ligand, a linker, and a BRAF inhibitor.
- Potent and selective degrader of CDK17 and LIMK2
- Exquisite selectivity and potency
- Advanced starting point for developing a chemical probe for CDK17 degradation
- For research use only
Medchemexpress LLC (S,R,S)-AHPC-Me-PEG2-dabrafenib | 2769753-69-5 | 99.9% | 1106.31 | 25 MG
DD-03-156 is a potent and selective degrader of CDK17 and LIMK2. Its selectivity and potency make it an advanced starting point for developing a chemical probe for the degradation of CDK17.
- Potent and selective degrader of CDK17 and LIMK2
- Advanced starting point for developing a chemical probe for CDK17 degradation
- Purity of 99.9%
- White to off-white solid appearance
- Consistent with structure by 1H NMR and LCMS
Medchemexpress LLC DHC-156 | 99.5% | 492.47 g·mol⁻¹ | C24H24F4N4O3 | 10 MG
DHC-156 is a selective small-molecule downmodulator of the transcription factor Brachyury, developed for preclinical research into chordoma. It downmodulates brachyury post-translationally and has been shown to impair chordoma cell growth. Intended for research use only.
- Selective downmodulator of the transcription factor Brachyury.
- Downmodulates brachyury post-translationally and impairs chordoma cell growth.
- Chemical formula: C24H24F4N4O3.
- Molecular weight: 492.47 g·mol⁻¹.
- High purity (99.5%).
- Available in multiple pack sizes, including 10 mg.
- Supplied for research use only; not for human or clinical use.