Boronic acid derivatives

Frontier Specialty Chemicals 1g, 3-Fluoro-5-methoxyphenylboronic acid, 98%, [609807-25-2], F2100 169.95 C7H8BFO3

Compound: 3-Fluoro-5-methoxyphenylboronic acid

CAS#: 609807-25-2

MDL#: MFCD07366780

Background: 3-Fluoro-5-methoxyphenylboronic acid is used for proteomics research and forms stable complexes with diols, making it an essential reagent in Suzuki-Miyaura cross-coupling reactions. It is used in the development of pharmaceuticals, agrochemicals, and advanced materials, as well as in biosensing and diagnostic applications due to its selective binding to specific biomolecules.

Frontier Specialty Chemicals 5g, 3-Fluoro-5-methoxyphenylboronic acid, 98%, [609807-25-2], F2100 169.95 C7H8BFO3

Compound: 3-Fluoro-5-methoxyphenylboronic acid

CAS#: 609807-25-2

MDL#: MFCD07366780

Background: 3-Fluoro-5-methoxyphenylboronic acid is used for proteomics research and forms stable complexes with diols, making it an essential reagent in Suzuki-Miyaura cross-coupling reactions. It is used in the development of pharmaceuticals, agrochemicals, and advanced materials, as well as in biosensing and diagnostic applications due to its selective binding to specific biomolecules.

Frontier Specialty Chemicals 1g, Isoquinoline-5-boronic acid, 96%, [371766-08-4], I2102 172.98 C9H8BNO2

Compound: Isoquinoline-5-boronic acid

CAS#: 371766-08-4

MDL#: MFCD03839356

Background: Isoquinoline-5-boronic acid is used in Suzuki-Miyaura cross-coupling reactions pivotal to the formation of carbon-carbon bonds in complex organic molecule synthesis. It serves as a building block in pharmaceutical development targeting cancer and other diseases, and is used in bioconjugation, fluorescent probe development for biological imaging, and advanced materials research.

Frontier Specialty Chemicals 5g, Isoquinoline-5-boronic acid, 96%, [371766-08-4], I2102 172.98 C9H8BNO2

Compound: Isoquinoline-5-boronic acid

CAS#: 371766-08-4

MDL#: MFCD03839356

Background: Isoquinoline-5-boronic acid is used in Suzuki-Miyaura cross-coupling reactions pivotal to the formation of carbon-carbon bonds in complex organic molecule synthesis. It serves as a building block in pharmaceutical development targeting cancer and other diseases, and is used in bioconjugation, fluorescent probe development for biological imaging, and advanced materials research.

Apexbio Technology LLC Pemetrexed disodium hemipenta hydrate 357166-30-4 200mg

Pemetrexed disodium hemipenta hydrate (CAS 357166-30-4) is a multitargeted antifolate that inhibits key enzymes in folate metabolism including thymidylate synthase (TS) dihydrofolate reductase (DHFR) and glycinamide ribonucleotide formyltransferase (GARFT) with Ki values for its pentaglutamate form of 1 3 nM 7 2 nM and 65 nM respectively Compared to the monoglutamate form the pentaglutamate exhibits enhanced inhibitory potency particularly against TS and GARFT Pemetrexed is approved for the treatment of advanced non-squamous non-small cell lung cancer In preclinical models it additionally modulates renal uptake of radiolabeled folates These features support its utilization in studies of folate pathway inhibition and cancer therapy