Naphthalenes
1-Naphthol (alpha-Naphthol; 1-Hydroxynaphthalene), Reagents
CAS: 90-15-3 Molecular Formula: C10H8O Molecular Weight (g/mol): 144.17 InChI Key: KJCVRFUGPWSIIH-UHFFFAOYSA-N Synonym: 1-Naphthalenol IUPAC Name: naphthalen-1-ol SMILES: OC1=C2C=CC=CC2=CC=C1
Selleck Chemical LLC BI-3231-E1875-100MG
BI-3231 is the potent and selective chemical probe which inhibits hydroxysteroid 17 -dehydrogenase 13 (HSD17B13) with an IC50 of 1 nM and Ki of 0 7 nM in the enzymatic assay It has the potential to treat NASH and other liver diseases
Selleck Chemical LLC BI-1347 S1058-25mg
BI-1347 is a small molecule inhibitor of Cyclin-dependent kinase 8(CDK8) with IC50 of 1 1 nM
Selleck Chemical LLC BI-D1870 S2843-50mg
BI-D1870 is an ATP-competitive inhibitor of S6 ribosome for RSK1/2/3/4 with IC50 of 31 nM/24 nM/18 nM/15 nM in cell-free assays respectively 10- to 100-fold selectivity for RSK than MST2 GSK-3 MARK3 CK1 and Aurora B BI-D1870 exhibits anticancer attributes including the generation of reactive oxygen species (ROS) and increases in endoplasmic reticulum (ER) stress and autophagy
Selleck Chemical LLC Adapalene S1276-25mg
Adapalene (CD-271) is a dual RAR and RXR agonist used in the treatment of acne
Selleck Chemical LLC Allylthiourea 50mg 109-57-9
Allylthiourea is a metabolic inhibitor that selective inhibits ammonia oxidation. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Adapalene S1276-100mg
Adapalene (CD-271) is a dual RAR and RXR agonist used in the treatment of acne
Selleck Chemical LLC BI-1347 S1058-1g
BI-1347 is a small molecule inhibitor of Cyclin-dependent kinase 8(CDK8) with IC50 of 1 1 nM
Selleck Chemical LLC BLU-945-E1176-100MG
BLU-945 is a potent highly selective reversible and orally active epidermal growth factor receptor(EGFR) tyrosine kinase inhibitor (TKIs) BLU-945 can be used for the research of lung cancer including non-small cell lung cancer (NSCLC)
Selleck Chemical LLC BI-2493-E1564-5MG
BI-2493 a structural analogue of BI-2865 is a highly selective inhibitor of pan-KRAS BI-2493 attenuates tumor growth and can be used for cancer research
Selleck Chemical LLC BLU-945-E1176-5MG
BLU-945 is a potent highly selective reversible and orally active epidermal growth factor receptor(EGFR) tyrosine kinase inhibitor (TKIs) BLU-945 can be used for the research of lung cancer including non-small cell lung cancer (NSCLC)
Selleck Chemical LLC BI-0474-E1356-5MG
BI-0474 is a potent inhibitor of KRASG12C with an IC50 value of 7 0 nM It inhibits GDP-KRAS SOS1 protein-protein interactions It exhibits anti-proliferative and anti-tumour activity and can be used in cancer research
Selleck Chemical LLC BI-D1870 S2843-1g
BI-D1870 is an ATP-competitive inhibitor of S6 ribosome for RSK1/2/3/4 with IC50 of 31 nM/24 nM/18 nM/15 nM in cell-free assays respectively 10- to 100-fold selectivity for RSK than MST2 GSK-3 MARK3 CK1 and Aurora B BI-D1870 exhibits anticancer attributes including the generation of reactive oxygen species (ROS) and increases in endoplasmic reticulum (ER) stress and autophagy
Selleck Chemical LLC BLU-945-E1176-10MM/1ML
BLU-945 is a potent highly selective reversible and orally active epidermal growth factor receptor(EGFR) tyrosine kinase inhibitor (TKIs) BLU-945 can be used for the research of lung cancer including non-small cell lung cancer (NSCLC)
Selleck Chemical LLC BI 1015550-E1382-25MG
BI 1015550 is an orally active inhibitor of PDE4B with IC50 of 7 2 nM It has good safety and potential applications in inflammation allergic diseases pulmonary fibrosis and chronic obstructive pulmonary disease (COPD)