Organoheterocyclic compounds
![Echelon Biosciences Research Labs Endothelin Receptor Antagonist BQ 3020; Acetyl-[Ala11,15]-ET 1 (6-21) - 0.5 mg, CAS#: 143113-45-5](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Echelon Biosciences Research Labs Endothelin Receptor Antagonist BQ 3020; Acetyl-[Ala11,15]-ET 1 (6-21) - 0.5 mg, CAS#: 143113-45-5
Endothelin Receptor Antagonist BQ 3020; Acetyl-[Ala11,15]-ET 1 (6-21) - 0.5mg , Ac-Leu-Met-Asp-Lys-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp-OH This item is non returnable
Innovative Research Inc Ms Fctr XII Rcmb 100ug
Mouse Factor XII Recombinant 100ug - Mouse Factor XII Recombinant from Innovative Research has been recombinantly produced in insect cells and purified using a combination of several chromatographic steps. This is a frozen liquid buffered in 4 mM Sodium Acetate; 0.15 M NaCl; pH 5.3 and a purity of >95%. This product is useful as a positive control for ELISA and western blot and for a variety of in vitro applications including cell signaling, clotting assays, fibrinolysis, hemostasis studies, protein-protein interactions, and receptor binding. Activity is determined via complementation in an APTT clotting assay using Factor XII immuno-deficient human plasma. More Details Source Insect Cell Culture Purification Chromatographically purified Purity >95% Storage Conditions -70 C
Innovative Research Inc Ms FXII Rcmb 50ug
Mouse Factor XII Recombinant 50ug - Mouse Factor XII Recombinant from Innovative Research has been recombinantly produced in insect cells and purified using a combination of several chromatographic steps. This is a frozen liquid buffered in 4 mM Sodium Acetate; 0.15 M NaCl; pH 5.3 and a purity of >95%. This product is useful as a positive control for ELISA and western blot and for a variety of in vitro applications including cell signaling, clotting assays, fibrinolysis, hemostasis studies, protein-protein interactions, and receptor binding. Activity is determined via complementation in an APTT clotting assay using Factor XII immuno-deficient human plasma. More Details Source Insect Cell Culture Purification Chromatographically purified Purity >95% Storage Conditions -70 C
Research Products International Corp Acrylamide 5 KG
Acrylamide (C₃H₅NO) is a water-soluble monomer (71.08 g/mol) that forms polyacrylamide gels used in electrophoresis to separate proteins and nucleic acids. It polymerizes with bis-acrylamide and initiators like APS and TEMED. Common applications in life science labs include SDS-PAGE, Western blotting, and nucleic acid analysis.
WARNING! This product can expose you to Acrylamide, a chemical which is known to the State of California to cause cancer, developmental and reproductive harm. For more information go to www.P65Warnings.ca.gov.
Research Products International Corp Acrylamide 10 KG
Acrylamide (C₃H₅NO) is a water-soluble monomer (71.08 g/mol) that forms polyacrylamide gels used in electrophoresis to separate proteins and nucleic acids. It polymerizes with bis-acrylamide and initiators like APS and TEMED. Common applications in life science labs include SDS-PAGE, Western blotting, and nucleic acid analysis.
WARNING! This product can expose you to Acrylamide, a chemical which is known to the State of California to cause cancer, developmental and reproductive harm. For more information go to www.P65Warnings.ca.gov.
Alkali Scientific Moxalactam, Sodium Salt, 500 Mg
Moxalactam Sodium Salt, in a 500mg format, is a beta-lactam antibiotic that is used in microbiological research to study bacterial resistance and antimicrobial susceptibility. It works by inhibiting the synthesis of bacterial cell walls, making it an essential tool for evaluating the effectiveness of antibiotics against both Gram-positive and Gram-negative bacteria. Moxalactam is often used in research settings to investigate beta-lactam resistance and to assess the potential of new antibiotics. Its wide spectrum of activity makes it a valuable agent for clinical research and laboratory studies focused on multidrug-resistant pathogens.
Medchemexpress LLC (2R)-N-(4-chlorophenyl)-2-((1s,4S)-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide | 1923833-60-6 | MFCD31729367 | ≥98.0% | 410.9 g/mol | C24H24ClFN2O | 50 MG
Linrodostat is a selective, orally available small-molecule inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1) used as a research reagent in immuno-oncology studies. It reduces production of the immunosuppressive metabolite kynurenine, enabling investigation of immune cell activation and tumor immunology.
- Selective inhibition of indoleamine 2,3-dioxygenase 1 for immuno-oncology research.
- Orally available small molecule reported in preclinical and clinical studies.
- High chemical purity suitable for biochemical and cellular assays.
- Well-characterized chemical identity and identifiers for reproducible research.
- Supplied in research-scale quantities for laboratory testing.
Medchemexpress LLC (R)-Zunsemetinib | 1640282-44-5 | 97.8% | 513.92 | 50 MG
(R)-Zunsemetinib is an isomer of Zunsemetinib, which serves as an experimental control. Zunsemetinib is an orally active and selective p38α mitogen-activated protein kinase-activated protein kinase 2 (MK2) pathway inhibitor. It is used for research on immuno-inflammatory diseases.
- Isomer of zunsemetinib
- Can be used as an experimental control
- Orally active and selective p38α mitogen-activated protein kinase-activated protein kinase 2 (MK2) pathway inhibitor
- Used for research of immuno-inflammatory diseases
Medchemexpress LLC Linrodostat | 1923833-60-6 | MFCD31619233; MFCD31729367 | 99.8% | 410.91 g·mol⁻¹ | C24H24ClFN2O | 10 MG
Linrodostat is a selective, irreversible indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor provided as a research-grade small molecule for preclinical in vitro and in vivo studies. It is used to investigate IDO1-mediated immunosuppression, kynurenine pathway modulation, and to support immuno-oncology and mechanistic pharmacology research.
- Selective irreversible IDO1 inhibition with low-nanomolar potency.
- High purity suitable for biochemical and cellular assays.
- Provided in a small pack size for exploratory studies.
- Soluble in DMSO for assay preparation and dosing.
- Applicable to immuno-oncology and mechanistic pharmacology research.
Alkali Scientific Cyanocobalamin (Vitamin B12), 50 G
Cyanocobalamin (Vitamin B12) is a vital biochemical reagent used in various applications, particularly in biochemical research and medical diagnostics. This 50g package is ideal for studies involving vitamin B12, which plays a key role in cellular metabolism and the synthesis of red blood cells. Vitamin B12 is widely utilized in research related to neurology, hematology, and metabolism. It is also used in clinical assays for the detection of B12 deficiency and related conditions such as anemia. This highly pure form of cyanocobalamin ensures precise, consistent results in laboratory analyses and provides researchers with a reliable resource for their experiments.
Medchemexpress LLC 3-amino-1-(3-(1-amino-2-hydroxyethyl)-1,2,4-oxadiazol-5-yl)-3-oxopropylcarbamoyl-L-threonine | 1673534-76-3 | MFCD30738000 | 99.9% | 360.32 g/mol | C12H20N6O7 | 50 MG
CA-170 is an orally available small-molecule antagonist of the immune checkpoint proteins VISTA and PD-L1, used in preclinical immuno-oncology research to restore T-cell proliferation and effector functions and to evaluate checkpoint modulation strategies.
- Orally available small-molecule inhibitor of VISTA and PD-L1.
- Restores T-cell proliferation and effector functions in cellular assays.
- Suitable for preclinical immuno-oncology and checkpoint modulation studies.
- Supplied as a high-purity research reagent for analytical and in vitro use.
- Stable when stored under recommended conditions for research purposes.
Alkali Scientific 5 Fluorouracil, 5 Grams
Fluorouracil (5-FU) is an anticancer agent widely used in laboratory research for its ability to inhibit DNA and RNA synthesis in cancer cells. Available in 5g quantities, this reagent is commonly used to study cell growth, gene expression, and cancer cell biology. 5-FU works by interfering with the synthesis of nucleotides, which are essential for DNA and RNA production. Its ability to inhibit cell division makes it useful for cancer research, particularly in studying tumor biology, cell cycle regulation, and drug resistance. The 5g quantity is ideal for smaller-scale experiments, allowing for efficient handling and use in oncology-related research.
Medchemexpress LLC Zunsemetinib | 1640282-42-3 | 99.99% | 513.92 | 1 G
Zunsemetinib is an orally active and selective p38α mitogen-activated protein kinase-activated protein kinase 2 (MK2) pathway inhibitor. It can be used for the research of immuno-inflammatory diseases.
- Orally active and selective MK2 pathway inhibitor
- Used for immuno-inflammatory disease research
- Reduces IL-1β secretion
- Promotes IL-1β mRNA instability
- Blocks LPS-induced TNF-α expression
- Increases bone density
- Prevents osteopenia
Apexbio Technology LLC Anti-LAG3/CD223-Ab-Relatlimab
Anti-LAG3/CD223 Antibody (Relatlimab) (CAS No 1673516-98-7) is a monoclonal antibody used in immuno-oncology research focusing on immune checkpoint inhibition Originating from biotechnology labs it targets the LAG-3 protein on T cells modulating immune response by blocking LAG-3 s interaction with MHC class II molecules This mechanism enhances T cell proliferation and activity playing a role in anti-tumor immunity Its in vitro activity ranges from nanomolar to low micromolar concentrations It is commonly applied in cell models animal studies and drug screening to investigate tumor immune evasion mechanisms and to develop cancer immunotherapies Experimental concentrations typically depend on the specific research design
Apexbio Technology LLC Anti-LAG3/CD223-Ab-Relatlimab
Anti-LAG3/CD223 Antibody (Relatlimab) (CAS No 1673516-98-7) is a monoclonal antibody used in immuno-oncology research focusing on immune checkpoint inhibition Originating from biotechnology labs it targets the LAG-3 protein on T cells modulating immune response by blocking LAG-3 s interaction with MHC class II molecules This mechanism enhances T cell proliferation and activity playing a role in anti-tumor immunity Its in vitro activity ranges from nanomolar to low micromolar concentrations It is commonly applied in cell models animal studies and drug screening to investigate tumor immune evasion mechanisms and to develop cancer immunotherapies Experimental concentrations typically depend on the specific research design