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LQZ-7I is a novel selectively inhibitor of survivin dimerization with IC50s of 4 8 M and 3 1 M in prostate cancer cell lines PC-3 and C4-2 respectively LQZ-7I orally effectively inhibits xenograft tumor growth and induces survivin loss in tumors
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KT-474 (SAR444656) is a selective small-molecule degrader of IRAK4 in development for the treatment of TLR/IL-1R driven autoimmune diseases KT-474 potently downregulates R848 (TLR7/8) and lipopolysaccharide (LPS)-induced IL-6 and IL-8 production in peripheral blood mononuclear cells (PBMCs)
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LLY-507 is a potent and selective inhibitor of protein-lysine methyltransferase SMYD2. It potently inhibits the ability of SMYD2 to methylate p53 peptide with an IC50 <15 nM. It serves as a valuable chemical probe to aid in the dissection of SMYD2 function in cancer and other biological processes.
Potent and selective inhibitor of protein-lysine methyltransferase SMYD2.
Inhibits SMYD2 to methylate p53 peptide with an IC50 <15 nM.
Valuable chemical probe for dissecting SMYD2 function in cancer and other biological processes.
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Perfluorodecyl bromide (PFDB) is a high-molecular-weight, lipophilic fluorocarbon used in chemical research and formulation. It is an analogue of perflubron and is commonly used to prepare phospholipid-stabilized fluorocarbon emulsions.
High-molecular-weight, lipophilic fluorocarbon
Used to prepare phospholipid-stabilized fluorocarbon emulsions
Solid at room temperature; molecular weight 598.98 g/mol
Chemical formula C10BrF21; CAS 307-43-7
Available in small laboratory quantities (for example, 50 mg)
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LLY-507 is a research-grade small-molecule inhibitor of the protein-lysine methyltransferase SMYD2, used as a chemical probe in epigenetics and cancer biology to study SMYD2-mediated methylation and downstream cellular effects.
Potent SMYD2 inhibition (IC50 <15 nM).
High purity (98.5%).
Chemical formula C36H42N6O; molecular weight 574.76 g/mol.
Available in small-molecule quantities, including 10 mg vials.
Supplied as solid with recommended DMSO solvent or as a pre-made DMSO solution.
For research use only; not for human or veterinary use.
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Sodium copper chlorophyllin B is a research chemical known for its antiviral activities against Influenza virus and HIV. It is supplied as a solid, black-green to black in color, and has a molecular weight of 738.13. This chemical is soluble in H2O and DMSO with the aid of ultrasonication.
Exerts antiviral activities against Influenza virus and HIV
Inhibits influenza virus adsorption at 200 μM
Inhibits HIV adsorption at 2.5 mM
Soluble in H2O and DMSO
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LLY-507 is a potent and selective inhibitor of protein-lysine methyltransferase SMYD2. It potently inhibits the ability of SMYD2 to methylate p53 peptide with an IC50 <15 nM. This compound serves as a valuable chemical probe to aid in the dissection of SMYD2 function in cancer and other biological processes.
Potent and selective inhibitor of SMYD2.
Inhibits SMYD2 from methylating p53 peptide with an IC50 <15 nM.
Useful chemical probe for dissecting SMYD2 function in cancer and other biological processes.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
LLY-507 is a potent and selective inhibitor of protein-lysine methyltransferase SMYD2. It potently inhibits the ability of SMYD2 to methylate p53 peptide with an IC50 <15 nM. LLY-507 serves as a valuable chemical probe to aid in the dissection of SMYD2 function in cancer and other biological processes. It is for research use only.
Potent and selective inhibitor of protein-lysine methyltransferase SMYD2.
Potently inhibits the ability of SMYD2 to methylate p53 peptide with an IC50 <15 nM.
Serves as a valuable chemical probe to aid in the dissection of SMYD2 function in cancer and other biological processes.
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Allyl-PEG2-OH is an allyl-terminated polyethylene glycol (PEG) derivative with a terminal hydroxyl group used as a short PEG linker in chemical synthesis, bioconjugation, and drug-delivery research. It is a low molecular weight PEG derivative commonly handled under cold storage conditions to preserve stability.
Allyl-terminated polyethylene glycol linker with a terminal hydroxyl group.
Molecular formula C7H14O3 and molecular weight 146.18 g/mol.
High purity (GC) 99.33%.
Suitable for chemical synthesis, bioconjugation, and drug-delivery linker design.
Storage: pure form -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
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hsa-let-7i-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs The miRNA antagomirs have 2 phosphorothioates at the 5 end 4 phosphorothioates at the 3 end 1 cholesterol group at the 3 end and full-length nucleotide 2 -methoxy modification The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes thereby inhibiting miRNAs from functioning Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors they exhibits enhanced cellular uptake stability and regulatory activity in vivo
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(R)-CPP is the R-enantiomer of CPP, a potent NMDA receptor antagonist used in research to study glutamatergic signaling and NMDA receptor pharmacology. It is provided as a high-purity solid for laboratory applications and is intended for research use only.
Potent NMDA receptor antagonist, more active isomer (R).
High purity suitable for sensitive pharmacological assays.
Supplied as a stable solid for convenient storage and handling.
Suitable for in vitro and in vivo research applications.
Well-characterized chemical identity (CAS 126453-07-4; MW 252.21 g/mol).
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