Hydrochlorides
Selleck Chemical LLC Nitrocaramiphen hydrochloride
Nitrocaramiphen hydrochloride is an antagonist of muscarinic acetylcholine receptor M1 (mAChR M1) which can completely remove the hyperpolarizing effect of muscarine
Selleck Chemical LLC Doxepin HCl S3120-25mg
Doxepin is a tricyclic antidepressant formulated as a mixture of E-(trans) and Z-(cis) stereoisomers It inhibits CYP2D6 activity in vivo
Selleck Chemical LLC Duloxetine S5071-25mg
Duloxetine (LY-248686) is a potent inhibitor of serotonin (5-hydroxytryptamine 5-HT) and noradrenaline (NE) uptake in vitro and in vivo and is 3- to 5-times more effective at inhibiting 5-HT uptake
Selleck Chemical LLC Duloxetine HCl S2084-100mg
Duloxetine HCl (LY-248686) is a serotonin-norepinephrine reuptake inhibitor with Ki of 4 6 nM used for treatment of major depressive disorder and generalized anxiety disorder (GAD)
Selleck Chemical LLC VU 0364770 S2862-10mg
VU 0364770 is a positive allosteric modulator(PAM) of mGlu4 with EC50 of 1 1 M exhibits insignificant activity at 68 other receptors including other mGlu subtypes
Selleck Chemical LLC N-Acetyl-5-hydroxytryptamine S2985-5mg
N-Acetyl-5-hydroxytryptamine (NAS N-Acetylserotonin Normelatonin O-Demethylmelatonin) a precursor of melatonin is a potent and selective agonist of TrkB receptor
Selleck Chemical LLC RS-127445 S2698-50mg
RS-127445 (MT500) is a selective 5-HT2B receptor antagonist with pKi of 9 5 and pIC50 of 10 4 exhibits 1000-fold selectivity against other 5-HT receptors
Selleck Chemical LLC VU-29 S1970-25mg
VU-29 is a positive allosteric modulator of metabotropic glutamate 5 (mGlu5) receptor with EC50 of 9 nM and Ki 244 nM for rat mGluR5 which is selective for mGluR5 relative to other mGluR subtypes
Selleck Chemical LLC Tirofiban S3085-5mg
Tirofiban (MK-383) is a selective platelet GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM
Selleck Chemical LLC Terbinafine S1725-1g
Terbinafine (SF 86-327 TDT 067) is used to treat infections caused by a fungus It works by killing the fungus or preventing its growth
Selleck Chemical LLC VU 0365114-E0799-5MG
VU 0365114 is a muscarinic acetylcholine receptor M5-preferring (mAChR M5-preferring) positive allosteric modulator (PAM) with an EC50 of 2 7 M
Selleck Chemical LLC VU 0364439
VU 0364439 is a mGlu4 positive allosteric modulator (PAM) with EC50 of 19 8 nM
Selleck Chemical LLC VU 0361737 S2892-10mg
VU 0361737 is a selective positive allosteric modulator (PAM) for mGlu4 receptor with EC50 of 240 nM and 110 nM at human and rat receptors respectively displays weak activity at mGlu5 and mGlu8 receptors is inactive at mGlu1 mGlu2 mGlu3 mGlu6 and mGlu7 receptors can penetrate into CNS
Selleck Chemical LLC VU 0357121 S2795-10mg
VU0357121 is a novel positive allosteric modulator (PAM) of mGlu5 with EC50 of 33 nM is inactive or very weakly antagonizing at other mGlu receptor subtypes
Selleck Chemical LLC Serotonin creatinine sulfate monohydrate S3344-25mg
Serotonin (5-Hydroxytryptamine) creatinine sulfate monohydrate is an active endogenous metabolite