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Positional and geometric isomers of fatty acids with conjugated double bonds; implies four consecutive unsaturated links, and results in a delocalization of electrons along the double-bonded carbons; available in carbon chains of varying length.
Itaconic acid a macrophage-specific (M -specific) metabolite mediates crosstalk between macrophage metabolism and peritoneal tumors Itaconic acid is also a precursor of polymers chemicals and fuels that can be synthesized by many fungi
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RK-701 is a highly selective potent and low-toxicity inhibitor of histone methyltransferases G9a and GLP1 with IC50 values of 23-27 nM and 53 nM RK-701 treatment induces fetal globin expression in human erythroid cells and in mice and plays an essential role in -globin induction RK-701 is used in the research of sickle cell disease
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Daminozide (Aminozide DMASA DIMG B 995 Alar Kylar B-NINE SADH) a plant growth regulator selectively inhibits the KDM2/7 JmjC subfamily with IC50 of 1 5 0 7 M for KDM2A It is at least 100-fold selective as an inhibitor of the KDM2/7 subfamily over the other demethylase subfamily members tested with IC50s of 2 M or less against KDM2A PHF8 and KIAA1718 and IC50s of 127 M for KDM3A or greater (mM range) against other demethylases
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Eicosapentaenoic acid (EPA) is an omega-3 polyunsaturated fatty acid with antiinflammatory properties and is present in fish and fish oils including salmon cod and krill oils
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Linoleic acid (9 12-octadecadienoic acid) is an essential fatty acid used in the biosynthesis of arachidonic acid and found in the lipids of cell membranes
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Fumaric acid (Fumarate 2-Butenedioic acid Trans-Butenedioic acid) is an intermediate in the citric acid cycle used by cells to produce energy in the form of adenosine triphosphate (ATP) from food also a product of the urea cycle
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Octanoic acid (caprylic acid) is found naturally in the milk of various mammals and as a minor constituent of coconut oil and palm kernel oil It is used in the production of esters used in perfumery and also in the manufacture of dyes
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RK-701 is a highly selective potent and low-toxicity inhibitor of histone methyltransferases G9a and GLP1 with IC50 values of 23-27 nM and 53 nM RK-701 treatment induces fetal globin expression in human erythroid cells and in mice and plays an essential role in -globin induction RK-701 is used in the research of sickle cell disease
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Fumaric acid (Fumarate 2-Butenedioic acid Trans-Butenedioic acid) is an intermediate in the citric acid cycle used by cells to produce energy in the form of adenosine triphosphate (ATP) from food also a product of the urea cycle
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More