Isotope Standards
Apexbio Technology LLC DOPAMINE-D4-HYDROCHLORIDE-10MG
Dopamine-d4 hydrochloride (CAS No 203633-19-6) is a deuterium-labeled derivative of dopamine commonly used in biomedical research to study dopaminergic pathways and neurotransmitter dynamics Originating from synthetic processes it acts primarily on dopamine receptors influencing pathways associated with neurological and psychiatric functions Its activity is typically observed in the nanomolar to low micromolar range making it suitable for precise mechanistic studies This compound is often utilized in vitro in cell models to investigate receptor interactions and in animal studies to explore behavioral and physiological effects It is also employed in drug screening programs to evaluate potential therapeutic agents targeting neurological conditions Experimental concentrations typically depend on the specific research design ensuring flexibility in various study protocols
Apexbio Technology LLC NAPHTHALENE-D8-100MG
Naphthalene-d8 (CAS No 1146-65-2) is a deuterated form of naphthalene often used in biomedical research for its stable isotopic labeling properties Originating from hydrocarbons it serves primarily in pharmacokinetic studies as a tracer due to its ability to integrate into various biological pathways without altering their function In vitro naphthalene-d8 is useful for analyzing metabolic processes often in nanomolar to low micromolar ranges It is commonly applied in cell models and animal studies to track and quantify metabolic changes improving the accuracy of drug screening and metabolic profiling Experimental concentrations typically depend on the specific research design
Apexbio Technology LLC ARIPIPRAZOLE-D8-5MG
Aripiprazole-d8 (CAS No 1089115-06-9) is a deuterated derivative of aripiprazole used in biomedical research primarily in pharmacokinetic and pharmacodynamic studies Originating as a tool compound it plays a role in understanding the mechanism of action related to dopamine D2 and serotonin 5-HT1A receptor modulation Common in vitro activities are noted in the nanomolar to low micromolar range reflecting its effectiveness in various binding assays It is utilized in cell models and animal studies serving as a valuable asset in drug screening to assess metabolic stability and bioavailability Experimental concentrations typically depend on the specific research design allowing flexibility in study parameters
Apexbio Technology LLC DIETHYLSTILBESTROL-D4-10MG
Diethylstilbestrol-d4 (CAS No 56-53-1) is a deuterium-labeled synthetic estrogen used primarily in biomedical research Originating as a derivative of diethylstilbestrol its mechanism of action involves binding to estrogen receptors influencing gene expression and cellular pathways related to growth and differentiation In vitro it exhibits activity typically in the nanomolar to low micromolar range This compound is frequently employed in cell models and animal studies specifically for endocrine and hormonal research It serves as a valuable tool in drug screening particularly for evaluating estrogenic and anti-estrogenic effects Experimental concentrations typically depend on the specific research design
Apexbio Technology LLC MOXIFLOXACIN-D4-1MG
Moxifloxacin-d4 (CAS No 2596386-23-9) is a deuterated derivative used in biomedical research primarily focused on bacteriology and pharmacokinetics Originating from synthetic modifications of the quinolone antibiotic moxifloxacin it functions by inhibiting bacterial DNA gyrase and topoisomerase IV essential enzymes for DNA replication This inhibition disrupts DNA processes leading to bacterial cell death Moxifloxacin-d4 exhibits potent antibacterial activity in vitro typically in the nanomolar to low micromolar range Its applications often include various cell models and animal studies to understand pharmacokinetics bioavailability and drug interaction Additionally it serves in drug screening processes to evaluate efficacy and metabolic pathways Experimental concentrations typically depend on the specific research design
Apexbio Technology LLC Imidacloprid 138261-41-3 100mg
Imidacloprid is a small-molecule modulator targeting nicotinic acetylcholine receptors (nAChRs) in insect nervous systems It is designed to selectively bind to nAChRs thereby disrupting cholinergic neurotransmission and neuronal signaling Imidacloprid exerts its biological activity primarily through interference with normal synaptic transmission by binding to nAChRs and causing abnormal neuronal signaling Based on these pharmacological properties Imidacloprid holds research potential in investigating cholinergic neurotransmission pathways receptor-ligand interactions neuronal signaling dysfunction neurotoxicity mechanisms and insecticide resistance It is also used as a comparative or reference molecule when characterizing the pharmacological or neurotoxicological profiles of candidate neuroactive compounds and insecticidal agents
Apexbio Technology LLC NAPHTHALENE-D8-50MG
Naphthalene-d8 (CAS No 1146-65-2) is a deuterated form of naphthalene often used in biomedical research for its stable isotopic labeling properties Originating from hydrocarbons it serves primarily in pharmacokinetic studies as a tracer due to its ability to integrate into various biological pathways without altering their function In vitro naphthalene-d8 is useful for analyzing metabolic processes often in nanomolar to low micromolar ranges It is commonly applied in cell models and animal studies to track and quantify metabolic changes improving the accuracy of drug screening and metabolic profiling Experimental concentrations typically depend on the specific research design
Apexbio Technology LLC QUETIAPINE-D8-FUMARATE-1MG
Quetiapine-d8 fumarate (CAS No 1185247-12-4) is a deuterium-labeled derivative of quetiapine fumarate commonly used in biomedical research for pharmacokinetic studies and drug metabolism investigations Originating from the antipsychotic family it functions by antagonizing neurotransmitter receptors such as serotonin 5-HT2A and dopamine D2 influencing neurotransmitter pathways and synaptic transmission Its in vitro activity typically ranges from nanomolar to low micromolar concentrations reflecting its effective binding at target sites Common applications include use in cell culture models animal studies and high-throughput drug screening where it helps elucidate the pharmacodynamics and pharmacokinetics of quetiapine Experimental concentrations typically depend on the specific research design allowing for tailored investigations to ascertain its therapeutic and side effect profiles
Apexbio Technology LLC ARIPIPRAZOLE-D8-1MG
Aripiprazole-d8 (CAS No 1089115-06-9) is a deuterated derivative of aripiprazole used in biomedical research primarily in pharmacokinetic and pharmacodynamic studies Originating as a tool compound it plays a role in understanding the mechanism of action related to dopamine D2 and serotonin 5-HT1A receptor modulation Common in vitro activities are noted in the nanomolar to low micromolar range reflecting its effectiveness in various binding assays It is utilized in cell models and animal studies serving as a valuable asset in drug screening to assess metabolic stability and bioavailability Experimental concentrations typically depend on the specific research design allowing flexibility in study parameters
Apexbio Technology LLC RISPERIDONE-D4-1MG
Risperidone-d4 (CAS No 1020719-76-9) is commonly used in biomedical research as a stable isotopic label of risperidone which enhances mass spectrometry analysis in pharmacokinetic studies Originating from the antipsychotic class of drugs it acts by antagonizing dopamine D2 and serotonin 5-HT2A receptors which are critical pathways in neurological disorders In vitro activity of risperidone-d4 typically ranges from nanomolar to low micromolar concentrations highlighting its high potency It is often applied in various research settings including cell models to assess drug metabolism animal studies for understanding therapeutic effects and drug screening to evaluate efficacy and safety profiles of new compounds Experimental concentrations typically depend on the specific research design
Apexbio Technology LLC QUETIAPINE D8 HEMIFUM-1mg
Quetiapine-d8 Hemifumarate (piperazine-d8) (CAS No 1435938-24-1) is a deuterated derivative of Quetiapine which is commonly used in biomedical research for its antipsychotic properties Originating from the piperazine class it primarily targets dopamine D2 and serotonin 5-HT2A receptors modulating neurotransmitter pathways to exert its effects This compound exhibits activity in the nanomolar to low micromolar range making it suitable for in vitro studies Quetiapine-d8 Hemifumarate is often applied in cellular models and animal studies to investigate psychiatric disorders and evaluate drug metabolism and pharmacokinetics in preclinical trials It is also useful in drug screening processes providing insights into therapeutic efficacy and safety Experimental concentrations typically depend on the specific research design
Apexbio Technology LLC Imidacloprid 138261-41-3 200mg
Imidacloprid is a small-molecule modulator targeting nicotinic acetylcholine receptors (nAChRs) in insect nervous systems It is designed to selectively bind to nAChRs thereby disrupting cholinergic neurotransmission and neuronal signaling Imidacloprid exerts its biological activity primarily through interference with normal synaptic transmission by binding to nAChRs and causing abnormal neuronal signaling Based on these pharmacological properties Imidacloprid holds research potential in investigating cholinergic neurotransmission pathways receptor-ligand interactions neuronal signaling dysfunction neurotoxicity mechanisms and insecticide resistance It is also used as a comparative or reference molecule when characterizing the pharmacological or neurotoxicological profiles of candidate neuroactive compounds and insecticidal agents
Sigma Organic Chemistry Cerilliant (±)-Epinephrine-D6 Solution, Certified Reference Material, 100 µg/mL, 1 mL
(±)-Epinephrine-D6 solution is a certified reference material used as an internal standard for the quantification of catecholamine levels in clinical samples. It is suitable for diagnostic testing in endocrinology, specifically for monitoring markers associated with pheochromocytoma, paraganglioma, and neuroblastoma via LC-MS/MS or GC-MS techniques.
- Provided as a 100 μg/mL single component solution in methanol with 5% 1 M HCl.
- Supplied in a 1 mL ampule for convenient use.
- Features Snap-N-Spike technology for reliable analytical performance.
- Suitable for both liquid chromatography and gas chromatography applications.
- Requires storage at −70°C in an ultra freezer.
