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Short chains of amino acids linked by peptide (amide) bonds. Peptides are used as catalysts, signaling ligands, and imaging agents; for biometric hydrogel construction, immunoprecipitation processes, and more.
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Neuropeptide Y (NPY), a 36 amino acid peptide widely distributed within central nervous system neurons, is a neuroprotective agent against β-amyloid neurotoxicity which influences the synthesis and the release of nerve growth factor (NGF) by cortical neurons.
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RGD peptide (GRGDNP) is an inhibitor of binding of integrins to the extracellular matrixs. RGD peptide (GRGDNP) induces apoptosis presumably through direct activation of caspase-3.
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Curcurbitacin IIA (Cucurbitacin Iia CuIIa Hemslecin A Dihydrocucurbitacin Q1) is a triterpene isolated from Hemsleya amalils Diels induces apoptosis of cancer cells reduces expression of survivin reduces phospho-Histone H3 and increases cleaved PARP in cancer cells
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Caulophylline (N-Methylcytisine Caulophyllin NMC) is a tricyclic quinolizidine alkaloid with anti-inflammatory activities Caulophylline binds to nicotinic acetylcholine receptors (nAChR) from squid optical ganglia with Kd of 50 nM Caulophylline significantly reduces myeloperoxidase (MPO) activity blocks the activation of NF- B by inhibiting I B and IKK phosphorylation
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740 Y-P is cell-permeable phosphopeptide activator of PI3K. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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PACAP 6-38 acetate is a PACAP (pituitary adenylate cyclase-activating polypeptide) non-stimulating competitive antagonist with an IC50 value of 2 nM. It also acts as a functional CARTp antagonist in vivo.
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Melittin (MLT, Forapin, Forapine) is an activator of phospholipase A2 (PLA2) that stimulates the activity of the low molecular weight PLA2, while it does not the increase the activity of the high molecular weight enzyme.
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Vitexin-2-O-rhamnoside (2 -O-Rhamnosylvitexin Apigenin-8-C-glucoside) is one of the main components of flavonoid of the leaves of Crataegus pinnatifida Bge var major N E Br It has many biological and pharmacological activities such as antioxidation and treating heart disease
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Cilengitide (EMD 121974, EMD-12192, EMD-85189, NSC-707544) is a potent and selective inhibitor of the integrins ανβ3 and ανβ5 with IC50 of 4 and 79 nM, respectively.
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