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ACROBiosystems Human TL1A-DR3 Inhibition Kit (TR-FRET), 100 tests
Human TL1A-DR3 Inhibition Kit (TR-FRET) is a homogeneous, no-wash competition assay for rapid screening of inhibitors that block TL1A binding to DR3. The assay uses time-resolved fluorescence resonance energy transfer for sensitive, high-throughput detection and produces results within 0.5-1 hour.
- Homogeneous competition TR-FRET assay for inhibitor screening.
- Available in 100-test and 500-test kit sizes; larger quantities by inquiry.
- Includes Europium-chelate labeled TL1A, FA-labeled DR3, control antibody, and TR-FRET buffers.
- Assay time 0.5-1 hour; typical completion in 1 hour.
- Store unopened kit at 2-8 °C; opened kit stable for 30 days.
- Validated with antibody inhibitors; demonstrated IC50 values in the low nanomolar range.
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ACROBiosystems Human TL1A-DR3 inhibition Kit (TR-FRET) is expressed from Human, 10000 tests
Human TL1A-DR3 inhibition Kit (TR-FRET) is expressed from Human
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ACROBiosystems Human DR3 Protein, Fc Tag (MALS verified), 1 mg
Human DR3 Protein, Fc Tag (MALS verified) is the extracellular domain of human death receptor 3 (DR3/TNFRSF25), expressed in HEK293 cells and fused to an Fc tag. The protein is verified by SEC-MALS and provided at high purity for use in binding assays, assay development, and antibody characterization.
- Expressed in HEK293 human cells for mammalian glycosylation.
- Contains amino acids Gln 25-Gln 199, matching the extracellular domain.
- Fc tag enables dimerization and detection in immunoassays.
- Purity greater than 95% as measured by size-exclusion chromatography.
- Molecular weight approximately 95-115 kDa confirmed by SEC-MALS.
- Supplied as a 1 mg quantity for laboratory use.