Amino Acids
Thermo Scientific Chemicals L(+)-Glutamic acid monosodium salt monohydrate, 99%
CAS: 6106-04-03 Molecular Formula: C5H8NNaO4·H2O Molecular Weight (g/mol): 187.13 MDL Number: MFCD00150138 InChI Key: GJBHGUUFMNITCI-QTNFYWBSSA-M
Oseltamivir phosphate, 98%, Thermo Scientific Chemicals
CAS: 204255-11-8 Molecular Formula: C16H28N2O4·H3PO4 Molecular Weight (g/mol): 410.4 InChI Key: PGZUMBJQJWIWGJ-ONAKXNSWSA-N Synonym: oseltamivir phosphate,tamiflu,oseltamir phosphate,unii-4a3o49ngez,4a3o49ngez,ethyl 3r,4r,5s-4-acetamido-5-amino-3-pentan-3-yloxy cyclohex-1-ene-1-carboxylate phosphate,ethyl 3r,4r,5s-4-acetamido-5-amino-3-1-ethylpropoxy-1-cyclohexene-1-carboxylate phosphate 1:1,osteltamivir phosphate,3r-3alpha,4beta,5alpha-ethyl 4-acetylamino-5-amino-3-1-ethylpropoxy-1-cyclohexene-1-carboxylate phosphate 1:1 PubChem CID: 78000 ChEBI: CHEBI:7799 IUPAC Name: ethyl (3R,4R,5S)-4-acetamido-5-amino-3-pentan-3-yloxycyclohexene-1-carboxylate;phosphoric acid SMILES: CCC(CC)OC1C=C(CC(C1NC(=O)C)N)C(=O)OCC.OP(=O)(O)O
Glycine, 98%, extra pure, Thermo Scientific Chemicals
CAS: 56-40-6 Molecular Formula: C2H5NO2 Molecular Weight (g/mol): 75.07 MDL Number: MFCD00008131 InChI Key: DHMQDGOQFOQNFH-UHFFFAOYSA-N Synonym: glycine,aminoacetic acid,glycocoll,aminoethanoic acid,glycolixir,glycosthene,aciport,glicoamin,padil,hampshire glycine PubChem CID: 750 ChEBI: CHEBI:15428 IUPAC Name: 2-aminoacetic acid SMILES: NCC(O)=O
D-Lysine, Thermo Scientific™
Thermo Scientific Chemicals L(+)-Asparagine monohydrate, 99%
CAS: 5794-13-8 Molecular Formula: C4H10N2O4 Molecular Weight (g/mol): 150.134 MDL Number: MFCD00151038 InChI Key: RBMGJIZCEWRQES-DKWTVANSSA-N Synonym: l-asparagine monohydrate,l +-asparagine monohydrate,l-asparagine hydrate,asparagine monohydrate,h-asn-oh.h2o,l-asparagine, monohydrate,asparagine nf,s-2,4-diamino-4-oxobutanoic acid hydrate,asparagine,unii-2pd79vf521 PubChem CID: 170358 IUPAC Name: (2S)-2,4-diamino-4-oxobutanoic acid;hydrate SMILES: C(C(C(=O)O)N)C(=O)N.O
Thermo Scientific Chemicals L(-)-Tryptophan, 99%
CAS: 73-22-3 Molecular Formula: C11H12N2O2 Molecular Weight (g/mol): 204.23 MDL Number: MFCD00064340 InChI Key: QIVBCDIJIAJPQS-VIFPVBQESA-N Synonym: l-tryptophan,tryptophan,l-tryptophane,s-tryptophan,tryptophane,h-trp-oh,optimax,trofan,tryptacin,ardeytropin PubChem CID: 6305 ChEBI: CHEBI:16828 IUPAC Name: (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid SMILES: N[C@@H](CC1=CNC2=CC=CC=C12)C(O)=O
Glycine, PlusOne™, Cytiva
CAS: 56-40-6 Molecular Formula: C2H5NO2 Molecular Weight (g/mol): 75.07 MDL Number: MFCD00008131 InChI Key: DHMQDGOQFOQNFH-UHFFFAOYSA-N Synonym: glycine,aminoacetic acid,glycocoll,aminoethanoic acid,glycolixir,glycosthene,aciport,glicoamin,padil,hampshire glycine PubChem CID: 750 ChEBI: CHEBI:15428 IUPAC Name: 2-aminoacetic acid SMILES: NCC(O)=O
ILEX LIFE SCIENCES LLC Ilex Life Sciences L-Asparaginase, E. coli Enzyme, Bioactive, 2,500 IU
Our high-purity, bioactive L-Asparaginase enzyme is purified from E. coli ASI.357. Purity: greater than 96%. Formulation: Lyophilized with no additives. Summary: L-Asparaginase is an enzyme that depletes L-Asparagine, an important nutrient for cancer cells, resulting in cancer/tumor cell starvation. The rationale behind asparaginase is that it takes advantage of the fact that acute lymphoblastic leukemia cells and some other suspected tumor cells are unable to synthesize the non-essential amino acid asparagine, whereas normal cells are able to make their own asparagine; thus leukemic cells depend on circulating asparagine. Asparaginase, however, catalyzes the conversion of L-asparagine to aspartic acid and ammonia. This deprives the leukemic cell of circulating asparagine, which leads to cell death. Synonyms: L-ASNase, L-asparagine amidohydrolase, ansA.
Enzo Life Sciences L-NAME . hydrochloride (5g). CAS: 51298-62-5
NOS inhibitor. Inhibitor of nitric oxide synthase (NOS). More soluble than NG-Nitro-L-arginine (ALX-105-001). Suppresses the release of nitric oxide (NO) from endothelial cells. Has a different effect on the superoxide generation by NOS than L-NMMA (ALX-106-001). Alternative name: NG-Nitro-L-arginine-methyl ester . HCl. Formula: C7H15N5O4 . HCl. MW: 233.2 . 36.5. Purity: ≥98% (TLC). Appearance: White to off-white solid. Solubility: Soluble in water (50mg/ml) or methanol (25g/ml). Long Term Storage: -20°C.
Enzo Life Sciences L-NAME . hydrochloride (25g). CAS: 51298-62-5
Inhibitor of nitric oxide synthase (NOS). More soluble than NG-Nitro-L-arginine (ALX-105-001). Suppresses the release of nitric oxide (NO) from endothelial cells. Has a different effect on the superoxide generation by NOS than L-NMMA (ALX-106-001). Alternative name: NG-Nitro-L-arginine-methyl ester . HCl. Formula: C7H15N5O4 . HCl. MW: 233.2 . 36.5. Purity: ≥98% (TLC). Appearance: White to off-white solid. Solubility: Soluble in water (50mg/ml) or methanol (25g/ml). Long Term Storage: -20°C.
Enzo Life Sciences N-Acetyl-Asp-Glu-OH (10mg). CAS: 3106-85-2
Endogenous neurotransmitter with high affinity for the brain glutamate receptor. N-acetylated α-linked acidic dipeptidase (NAALADase), a membrane-bound peptidase, hydrolyzes α-NAAG, a major brain peptide, to N-acetylaspartate and glutamate. Discriminates between mGluR2 and mGluR3. mGluR3 activator. NMDA receptor antagonist. Neuroprotective. Alternative name: alpha NAAG, Spaglumic acid. Formula: C11H16N2O8. MW: 304.3. Purity: ≥98% (TLC). Solubility: Soluble in water and methanol (50mg/ml). Long Term Storage: +4°C.
Enzo Life Sciences Z-Phe-Arg-pNA. hydrochloride (5mg). CAS: 59188-54-4
Chromogenic substrate for Cathepsins B, K, L, and S, papain, trypsin, and plasma kallikrein. This substrate is likely to be cleaved by other cathepsins (see Z-Phe-Arg-AMC). Release of pNA is monitored at 405-410 nm (pNA ε410=8800 M-1cm-1). Useful for inhibitor screening and kinetic analysis. Alternative name: Z-FR-pNA . HCl. Formula: C29H33N7O6 . HCl. MW: 575.6 . 36.5. Purity: ≥99% (TLC). Formulation: Lyophilized. Solubility: Soluble in methanol (50mg/ml) and DMSO. Long Term Storage: -20°C.
Enzo Life Sciences Boc-Ala-Ala-Nva-SBzl (5mg)
Much more sensitive substrate for leukocyte proteinase 3 (PR-3, myeloblastin) (Kcat/km=1.06 x 106 M-1s-1, Km=63 µM) than MeOSuc-AAPV-pNA (Chromogenic Substrate) (BML-P213) (Kcat/km=1.06 x 103 M-1s-1, Km=470 µM). Also cleaved by neutrophil elastase (Kcat/km=9.2 x 106 M-1s-1, Km=2.2 µM), granzyme H, cathepsin G, chymotrypsin, and rat MCPI and II. Typical assay conditions: substrate concentration 88-250 µM; enzyme concentration 0.2-20 nM; buffer [100 mM HEPES pH 7.5, 500 mM NaCl, 10% DMSO]; with 170 µM either 5,5'-dithiobis(2-nitrobenzoic acid) (DTNB) or 4,4'-dithiobis(pyridine) (from 15 mM DMSO stocks); 25°C. Hydrolysis of substrate can be detected at 412 nm for DTNB ( Purity: ≥95% (HPLC). Formulation: Lyophilized. Solubility: Soluble in DMSO (1mg/ml). Long Term Storage: -20°C.
Enzo Life Sciences E-64-D, (5mg), CAS Number: 88321-09-9
Calpain and cathepsin inhibitor. Cell-permeable, ethyl ester of E-64-c. The ester is hydrolyzed by intracellular esterases to produce E-64-c. Inhibits calpain and cathepsins B, H, and L. Inhibits degradation of autophagic cargo inside autophagolysosomes. Alternative Name: 2S,3S-trans-(Ethoxycarbonyloxirane-2-carbonyl)-L-leucine-(3-methylbutyl) amide. Aloxistatin. Formula: C17H30N2O5. MW: 342.4. CAS Number: 88321-09-9. Purity: ≥98% (HPLC). Appearance: White solid. Solubility: Soluble in 100% ethanol (>10mg/ml) or DMSO (20mg/ml). Use/Stability: Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 2 months. Long Term Storage: -20°C
Enzo Life Sciences N-Acetyl-S-farnesyl-L-cysteine (5mg). CAS: 135304-07-3
Members of the Ras superfamily of G proteins, γ-subunits of heterotrimeric G proteins and the α-subunit of cGMP phosphodiesterase from retinal rods are all carboxyl methylated at carboxy-terminal S-farnesylcysteine residues. AFC specifically inhibits the S-farnesylcysteine methyl transferase (Km=20 µM) in cell free extracts and in whole cells. It inhibits carboxyl methylation of p21ras platelet Rap15 and the γ-subunit of transducin. It blocks receptor-mediated signal transduction in platelets and neutrophils not by inhibiting the methyltransferase, but possibly by inhibiting capacitative Ca2+ entry. Alternative name: AFC. Purity: ≥98% (HPLC). Solubility: Soluble in DMSO (25mg/ml), methanol or 100% ethanol (25mg/ml). Long Term Storage: -20°C.